country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-149980

Copy Link Print Information

DCN-83

DCN-83, an anti-leishmania agent, is most potent against the amastigote form with an IC₅₀ of 0.71 μM. DCN-83 has the potential to cross the blood-brain barrier and central nervous system.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₀H₁₈BrN₃S
Peso molecular:412.35

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

DCN-83 Chemical Structure

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

DCN-83, an anti-leishmania agent, is most potent against the amastigote form with an IC₅₀ of 0.71 μM. DCN-83 has the potential to cross the blood-brain barrier and central nervous system^[1].

Ver todos los productos específicos de isoformas Parasite :

Cellular Effect

Cell Line	Type	Value	Description	References
J774.A1	CC₅₀	>100 μM Compound: 8CN-83	Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay	[PMID: 36848847]

In Vitro

DCN-83 has no AMES toxicity and hepatotoxicity^[1].
DCN-83 has a slight inhibitory effect on Macrophage J774.A1, with a CC₅₀ value of 84.73 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Peso molecular 412.35
Fòrmula C₂₀H₁₈BrN₃S
SMILES

N#CC1=C(SC2=C1CCCCCC2)/N=C/C3=CNC4=C3C=C(C=C4)Br
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Luna IS, et al. Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents. Eur J Med Chem. 2023 Mar 15;250:115223. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Obtener un presupuesto En stock

Amount: USD 0.00

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

DCN-83

Ver todos los productos específicos de isoformas Parasite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

DCN-83 Related Classifications

HY-149980 Related Classifications