DCPT1061
Based on 1 Customer Validation
DCPT1061 potently inhibits PRMT1, PRMT6 and PRMT8 in vitro with less inhibitory effect on PRMT3, PRMT4, and PRMT5 or other epigenetic enzymes. DCPT1061 has antitumor effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.81%
- No. CAS: 2289726-31-2
- Fòrmula: C17H20Cl2N2O
- Peso molecular:339.26
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Almacenamiento:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas Histone Methyltransferase
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2289726-31-2
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Appearance Liquid (Density: 1.201±0.06 g/cm3)
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Peso molecular 339.26
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Fòrmula C17H20Cl2N2O
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Color Colorless to light yellow
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SMILES
ClC1=C(OC2=CC=CC=C2CN(C)CCNC)C=CC=C1Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : ≥ 250 mg/mL (736.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Jianfeng Wang, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 2021 Mar 12;11(11):5387-5403. [Content Brief]
[2]. Hongru Tao, et al. PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma. Cancer Res. 2023 Nov 22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9476 mL | 14.7380 mL | 29.4759 mL | 73.6898 mL |
| 5 mM | 0.5895 mL | 2.9476 mL | 5.8952 mL | 14.7380 mL | |
| 10 mM | 0.2948 mL | 1.4738 mL | 2.9476 mL | 7.3690 mL | |
| 15 mM | 0.1965 mL | 0.9825 mL | 1.9651 mL | 4.9127 mL | |
| 20 mM | 0.1474 mL | 0.7369 mL | 1.4738 mL | 3.6845 mL | |
| 25 mM | 0.1179 mL | 0.5895 mL | 1.1790 mL | 2.9476 mL | |
| 30 mM | 0.0983 mL | 0.4913 mL | 0.9825 mL | 2.4563 mL | |
| 40 mM | 0.0737 mL | 0.3684 mL | 0.7369 mL | 1.8422 mL | |
| 50 mM | 0.0590 mL | 0.2948 mL | 0.5895 mL | 1.4738 mL | |
| 60 mM | 0.0491 mL | 0.2456 mL | 0.4913 mL | 1.2282 mL | |
| 80 mM | 0.0368 mL | 0.1842 mL | 0.3684 mL | 0.9211 mL | |
| 100 mM | 0.0295 mL | 0.1474 mL | 0.2948 mL | 0.7369 mL |
DCPT1061 Related Classifications
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