DCPT1061 hydrochloride
Based on 1 Customer Validation
DCPT1061 hydrochloride has a strong inhibitory effect on PRMT1, PRMT6, and PRMT8 in vitro, The epigenetic enzymes such as PRMT3, PRMT4 and PRMT5 had little inhibitory effect. DCPT1061 hydrochloride has antitumor effects.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.88%
- 分子式: C17H21Cl3N2O
- 分子量:375.72
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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性状 Solid
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分子量 375.72
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分子式 C17H21Cl3N2O
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Color White to off-white
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SMILES
ClC1=C(OC2=CC=CC=C2CN(C)CCNC)C=CC=C1Cl.[H]Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (133.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Wang J, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 2021 Mar 12;11(11):5387-5403. [Content Brief]
[2]. Tao H, et al. PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma. Cancer Res. 2023 Nov 22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6616 mL | 13.3078 mL | 26.6156 mL | 66.5389 mL |
| 5 mM | 0.5323 mL | 2.6616 mL | 5.3231 mL | 13.3078 mL | |
| 10 mM | 0.2662 mL | 1.3308 mL | 2.6616 mL | 6.6539 mL | |
| 15 mM | 0.1774 mL | 0.8872 mL | 1.7744 mL | 4.4359 mL | |
| 20 mM | 0.1331 mL | 0.6654 mL | 1.3308 mL | 3.3269 mL | |
| 25 mM | 0.1065 mL | 0.5323 mL | 1.0646 mL | 2.6616 mL | |
| 30 mM | 0.0887 mL | 0.4436 mL | 0.8872 mL | 2.2180 mL | |
| 40 mM | 0.0665 mL | 0.3327 mL | 0.6654 mL | 1.6635 mL | |
| 50 mM | 0.0532 mL | 0.2662 mL | 0.5323 mL | 1.3308 mL | |
| 60 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1090 mL | |
| 80 mM | 0.0333 mL | 0.1663 mL | 0.3327 mL | 0.8317 mL | |
| 100 mM | 0.0266 mL | 0.1331 mL | 0.2662 mL | 0.6654 mL |
DCPT1061 hydrochloride 関連分類
HY-162003A 関連分類
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