DCPT1061 hydrochloride
Based on 1 Customer Validation
DCPT1061 hydrochloride has a strong inhibitory effect on PRMT1, PRMT6, and PRMT8 in vitro, The epigenetic enzymes such as PRMT3, PRMT4 and PRMT5 had little inhibitory effect. DCPT1061 hydrochloride has antitumor effects.
For research use only. We do not sell to patients.
- Purity: 99.88%
- Formula: C17H21Cl3N2O
- Molecular Weight:375.72
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Epigenetics Compound Library
HY-L005
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Histone Modification Research Compound Library
HY-L024
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Anti-Cancer Compound Library
HY-L025
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Reprogramming Compound Library
HY-L039
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Anti-Blood Cancer Compound Library
HY-L079
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Transcription Factor-Targeted Library
HY-L090
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Anti-Hematopathy Compound Library
HY-L171
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Methylation Compound Library
HY-L203
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 375.72
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Formula C17H21Cl3N2O
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Color White to off-white
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SMILES
ClC1=C(OC2=CC=CC=C2CN(C)CCNC)C=CC=C1Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (133.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang J, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 2021 Mar 12;11(11):5387-5403. [Content Brief]
[2]. Tao H, et al. PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma. Cancer Res. 2023 Nov 22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6616 mL | 13.3078 mL | 26.6156 mL | 66.5389 mL |
| 5 mM | 0.5323 mL | 2.6616 mL | 5.3231 mL | 13.3078 mL | |
| 10 mM | 0.2662 mL | 1.3308 mL | 2.6616 mL | 6.6539 mL | |
| 15 mM | 0.1774 mL | 0.8872 mL | 1.7744 mL | 4.4359 mL | |
| 20 mM | 0.1331 mL | 0.6654 mL | 1.3308 mL | 3.3269 mL | |
| 25 mM | 0.1065 mL | 0.5323 mL | 1.0646 mL | 2.6616 mL | |
| 30 mM | 0.0887 mL | 0.4436 mL | 0.8872 mL | 2.2180 mL | |
| 40 mM | 0.0665 mL | 0.3327 mL | 0.6654 mL | 1.6635 mL | |
| 50 mM | 0.0532 mL | 0.2662 mL | 0.5323 mL | 1.3308 mL | |
| 60 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1090 mL | |
| 80 mM | 0.0333 mL | 0.1663 mL | 0.3327 mL | 0.8317 mL | |
| 100 mM | 0.0266 mL | 0.1331 mL | 0.2662 mL | 0.6654 mL |
DCPT1061 hydrochloride Related Classifications
HY-162003A Related Classifications
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