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Galvokimig

(Synonyms: UCB-9741)
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Based on 1 Customer Validation

Galvokimig (UCB-9741) is an anti-IL-13/IL-17A/albumin (ALB)/IL-17F trispecific Fab-scFv fusion protein. Galvokimig simultaneously binds IL-13 and IL-17 with high affinity and has an extended half-life through albumin binding. Galvokimig inhibits IL-13-mediated, IL-17A-mediated, and IL-17F-mediated signaling. Galvokimig inhibits IL-17A- and IL-17F-induced IL-6 release in dermal fibroblasts and inhibits IL-19 and IL-24 production in primary epidermal keratinocytes. Galvokimig can be used for research on atopic dermatitis.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza : 99.71%
  • No. CAS: 2648456-30-6
  • Peso molecular:101.953 kDa
  • Almacenamiento:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Galvokimig
  • Experimental Validation Results for Galvokimig
  • Experimental Validation Results for Galvokimig
  • Experimental Validation Results for Galvokimig
  • Experimental Validation Results for Galvokimig
  • Galvokimig Chemical Structure
    Galvokimig Chemical Structure
No. CAS: 2648456-30-6
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Galvokimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-G1_kappa-scFv-heavy-kappa

  • 1/16

    Immobilized IL-13 Protein, Human (HEK293, His, HY-P70568) can bind Galvokimig. The EC50 for this effect is 941.7 ng/mL.

  • 1/16

    Immobilized IL-17A Protein, Human (HEK293, His, HY-P70527) can bind Galvokimig. The EC50 for this effect is 31.32 ng/mL.

  • 1/16

    Immobilized Serum Albumin/ALB Protein, Human (HEK293, His-Avi, HY-P78393) can bind Galvokimig. The EC50 for this effect is 10.4 ng/mL.

  • 1/16

    Immobilized IL-17F Protein, Human (HEK293, His, HY-P70540) can bind Galvokimig. The EC50 for this effect is 595.9 ng/mL.

  • Galvokimig Chemical Structure
    1/16
  • Galvokimig
  • Immobilized IL-13 Protein, Human (HEK293, His, HY-P70568) can bind Galvokimig. The EC50 for this effect is 941.7 ng/mL.
  • Immobilized IL-17A Protein, Human (HEK293, His, HY-P70527) can bind Galvokimig. The EC50 for this effect is 31.32 ng/mL.
  • Immobilized Serum Albumin/ALB Protein, Human (HEK293, His-Avi, HY-P78393) can bind Galvokimig. The EC50 for this effect is 10.4 ng/mL.
  • Immobilized IL-17F Protein, Human (HEK293, His, HY-P70540) can bind Galvokimig. The EC50 for this effect is 595.9 ng/mL.
  • Fab-G1_kappa-scFv-heavy-kappa