GEN-1053
Based on 1 Customer Validation
GEN-1053 (BNT-313) is a fully human IgG1 antibody that targets CD27. GEN-1053 binds to CD27 and forms a hexamer upon binding. The isotype control for GEN-1053 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.72%
- No. CAS: 2733575-82-9
- Peso molecular:143.727 kDa
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Almacenamiento:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD27
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-lambda
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD27/TNFRSF7 Protein, Human (HEK293, His-Fc, HY-P72742) can bind GEN-1053. The EC50 for this effect is 18.35 ng/mL.
Chemical Information
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No. CAS 2733575-82-9
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Appearance Liquid
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Peso molecular 143.727 kDa
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Color Colorless to light yellow
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SMILES
[GEN-1053]
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Synonyms
BNT-313; Tixestobart
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (254 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)