country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

CACNG1 - calcium voltage-gated channel auxiliary subunit gamma 1 Gene

Also Known as CACNLG

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 786

About CACNG1

Cytogenetic location: 17q24.2 Genomic coordinates (GRCh38): 17:67,044,554-67,056,797 (from NCBI)

This gene has 1 transcript (splice variant), 268 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 1.9), prostate (RPKM 1.8) and 2 other tissues.

Summary

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA Receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010]

CACNG1 Products (1)

mRNA	Protein	Name
NM_000727.4	NP_000718.1	voltage-dependent calcium channel gamma-1 subunit

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Referencias	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CACNG1 Protein Structure

Claudin_2

0
100
200
222 a.a.

Protein Preferred Names	Protein Names
voltage-dependent calcium channel gamma-1 subunit	L-type calcium channel gamma polypeptide

CACNG1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	CACNG1	Q06432	VAPA	Homo sapiens	Q9P0L0	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	VAPA	Homo sapiens	Q9P0L0	Validated Y2H	32296183
Intra	CACNG1	Q06432	VAPA	Homo sapiens	Q9P0L0	Y2H Array	32296183
Intra	CACNG1	Q06432	GPX8	Homo sapiens	Q8TED1	Validated Y2H	32296183
Intra	CACNG1	Q06432	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	CACNG1	Q06432	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	CACNG1	Q06432	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	CACNG1	Q06432	ODF4	Homo sapiens	Q2M2E3	Y2H Array	32296183
Intra	CACNG1	Q06432	ODF4	Homo sapiens	Q2M2E3	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	ODF4	Homo sapiens	Q2M2E3	Validated Y2H	32296183
Intra	CACNG1	Q06432	TLCD4	Homo sapiens	Q96MV1	Validated Y2H	32296183
Intra	CACNG1	Q06432	TLCD4	Homo sapiens	Q96MV1	Y2H Array	32296183
Intra	CACNG1	Q06432	TLCD4	Homo sapiens	Q96MV1	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	MUC1	Homo sapiens	P15941-11	Y2H Array	32296183
Intra	CACNG1	Q06432	MUC1	Homo sapiens	P15941-11	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	ERVFRD-1	Homo sapiens	P60508	Y2H Array	32296183
Intra	CACNG1	Q06432	ERVFRD-1	Homo sapiens	P60508	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	CPLX4	Homo sapiens	Q7Z7G2	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	CPLX4	Homo sapiens	Q7Z7G2	Validated Y2H	32296183
Intra	CACNG1	Q06432	CPLX4	Homo sapiens	Q7Z7G2	Y2H Array	32296183
Intra	CACNG1	Q06432	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	HSD17B13	Homo sapiens	Q7Z5P4	Validated Y2H	32296183
Intra	CACNG1	Q06432	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
Intra	CACNG1	Q06432	FFAR2	Homo sapiens	O15552	Y2H Array	32296183
Intra	CACNG1	Q06432	FFAR2	Homo sapiens	O15552	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	TMEM45B	Homo sapiens	Q96B21	Validated Y2H	32296183
Intra	CACNG1	Q06432	TMEM45B	Homo sapiens	Q96B21	Y2H Array	32296183
Intra	CACNG1	Q06432	TMEM45B	Homo sapiens	Q96B21	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	BIK	Homo sapiens	Q13323	Y2H Array	32296183
Intra	CACNG1	Q06432	BIK	Homo sapiens	Q13323	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	BIK	Homo sapiens	Q13323	Validated Y2H	32296183
Intra	CACNG1	Q06432	MGST3	Homo sapiens	O14880	Y2H Array	32296183
Intra	CACNG1	Q06432	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	THAP4	Homo sapiens	Q8WY91	Validated Y2H	32296183
Intra	CACNG1	Q06432	THAP4	Homo sapiens	Q8WY91	Y2H Array	32296183
Intra	CACNG1	Q06432	THAP4	Homo sapiens	Q8WY91	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	REEP4	Homo sapiens	Q9H6H4	Validated Y2H	32296183
Intra	CACNG1	Q06432	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
Intra	CACNG1	Q06432	GAD2	Homo sapiens	Q05329	Y2H Prey Pooling	32296183
Intra	CACNG1	Q06432	GAD2	Homo sapiens	Q05329	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Malignant Hyperthermia	Anesthesia Related Hyperthermia Malignant Hyperpyrexia Due To Anesthesia Hyperpyrexia, Malignant Hyperthermia, Malignant Malignant Hyperpyrexia Mhs Malignant Fever
Autosomal Dominant Nonsyndromic Deafness 78	Dfna78
Arrhythmogenic Right Ventricular Cardiomyopathy	Arrhythmogenic Right Ventricular Dysplasia Arvc Arvd Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Arvc Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia Arvd/C Right Ventricular Dysplasia, Arrhythmogenic Ventricular Dysplasia, Right, Arrhythmogenic Cardiomyopathy, Ventricular, Right, Arrhythmogenic Dysplasia, Arrhythmogenic Right Ventricular
Cenani-Lenz Syndactyly Syndrome	Syndactyly Type 7 Cenani Syndactylism Cenani-Lenz Syndactyly CLSS Syndactyly Cenani Lenz Type Cenani-Lenz Syndrome Syndactyly, Type Vii Cenani-Lenz Type Syndactyly Cenani Syndactyly Syndactyly Type Vii
Hypokalemic Periodic Paralysis, Type 1	Hypokalemic Periodic Paralysis Hokpp Hypopp Westphall Disease HOKPP1 Familial Hypokalemic Periodic Paralysis Familial Periodic Paralysis Westphal Disease Hypokalemic Periodic Paralysis Type 1 Hypokalemic Familial Periodic Paralysis Periodic Hypokalemic Paralysis Periodic Paralysis I Hypokpp Primary Hypokalemic Periodic Paralysis Periodic Paralysis Hypokalemic 1 Paralysis, Hypokalemic, Periodic Paralysis, Hypokalemic, Periodic, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-RS01809	CACNG1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CACNG1	VGNC	VGNC:26686
Rattus norvegicus	CACNG1	RGD	RGD:2249
Canis familiaris	CACNG1	VGNC	VGNC:38647
Mus musculus	CACNG1	MGD	MGI:1206582
Felis catus	CACNG1	VGNC	VGNC:98775
Macaca mulatta	CACNG1	VGNC	VGNC:82117
Others	CACNG1	NCBI