GQN-B37-E
GQN-B37-E is a potent selective binder and inhibitor of MCL-1. GQN-B37-E binds to the BH3-domain-binding pocket in MCL-1. GQN-B37-E exhibits binding affinity for MCL-1 at the submicromolar range (Ki = 0.6 μM) without apparent binding to BCL-2 or BCL-XL.
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- No. CAS: 2982663-28-3
- Fòrmula: C29H23ClN4O4
- Peso molecular:526.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Mcl-1 0.6 μM (Ki) |
Chemical Information
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No. CAS 2982663-28-3
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Peso molecular 526.97
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Fòrmula C29H23ClN4O4
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SMILES
O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC(/C=C/C3=CN(C4=CC=CC(Cl)=C4)N=C3C5=CC=C(O)C=C5)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GQN-B37-E Related Classifications
HY-161732 Related Classifications
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