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Referencia número: HY-N3246

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Morachalcone A

Name: Morachalcone A
Brand: MedChemExpress
SKU: HY-N3246
Price: 1035.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Morachalcone A is a naturally-occurring aromatase inhibitor (IC₅₀=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production.

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No. CAS: 76472-88-3
Fòrmula: C₂₀H₂₀O₅
Peso molecular:340.37

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Morachalcone A Chemical Structure

No. CAS: 76472-88-3

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- Cellular Effect
- In Vitro
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Descripciòn

Ver todos los productos específicos de isoformas NO Synthase :

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	16.4 μM Compound: 3	Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs	[PMID: 16643064]
RAW264.7	IC₅₀	58 μM Compound: 3	Cytotoxicity against mouse RAW264.7 cells by MTT assay Cytotoxicity against mouse RAW264.7 cells by MTT assay	[PMID: 16643064]

In Vitro

Morachalcone A is the metabolite of Maclura pomifera (the Osage orange tree) and Hypericum Geminiflorum and Broussonetia papyrifera^[1].
Morachalcone A exhibites inhibitory activities against lipopolysaccharide-induced nitric oxide production in cultured RAW 264.7 cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 76472-88-3
Peso molecular 340.37
Fòrmula C₂₀H₂₀O₅
SMILES

OC(C=C(O)C=C1)=C1/C=C/C(C2=C(C(C/C=C(C)/C)=C(O)C=C2)O)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Brandt D R, et al. The synthetic preparation of naturally-occurring aromatase inhibitors, morachalcone A, isogemichalcone B, and isogemichalcone C[J]. Tetrahedron, 2013, 69(47): 9994-10002.

[2]. Kang Y J, et al. Inhibitory effects of morachalcone A on lipopolysaccharide-induced nitric oxide production in raw 264.7 cells[J]. 2009.

[3]. Ferlinahayati, et al. Phenolic constituents from the wood of Morus australis with cytotoxic activity. Z Naturforsch C J Biosci. 2008 Jan-Feb;63(1-2):35-9. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Morachalcone A

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Carboxy-PTIO potassium

2,4-Diamino-6-hydroxypyrimidine

L-NIL

Asperuloside

2-Thiouracil

L-NIO dihydrochloride

GW274150

S-Methylisothiourea sulfate

Apiin

2-Iminobiotin

Nω-Propyl-L-arginine

Ver todos los productos específicos de isoformas NO Synthase

Actividad biológica

Chemical Information

Pureza y Documentación

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Bioz

Morachalcone A

S-Nitroso-N-acetyl-DL-penicillamine

Carboxy-PTIO potassium

2,4-Diamino-6-hydroxypyrimidine

L-NIL

Asperuloside

2-Thiouracil

L-NIO dihydrochloride

GW274150

S-Methylisothiourea sulfate

Apiin

2-Iminobiotin

Nω-Propyl-L-arginine

Ver todos los productos específicos de isoformas NO Synthase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Morachalcone A Related Classifications

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