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Referencia número: HY-15101

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MV061194

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1021423-50-6
Fòrmula: C₂₈H₃₇N₅O₄S
Peso molecular:539.70

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

MV061194 Chemical Structure

No. CAS: 1021423-50-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

MV061194 is a selective cathepsin K inhibitor with a human K_i of 2.5 nM. MV061194 can be used for the research of osteoporosis^[1].

IC₅₀ & Target^[1]

cathepsin K

2.5 nM (Ki)

Ver todos los productos específicos de isoformas Cathepsin :

In Vitro

MV061194 potently and selectively inhibits recombinant human cathepsin K with a K_i of 2.5 nM, showing >4000-fold selectivity over multiple other cathepsin isoforms^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1021423-50-6
Peso molecular 539.70
Fòrmula C₂₈H₃₇N₅O₄S
SMILES

C(N[C@H]1[C@H](CC)OCC1=O)(=O)C2(NC(=O)C3=CC=C(C=C3)C=4N=C(SC4)N5CCN(C)CC5)CCCCC2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Allen J G, et al. Emerging targets in osteoporosis disease modification[J]. Journal of medicinal chemistry, 2010, 53(11): 4332-4353. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias

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MV061194

Ver todos los productos específicos de isoformas Cathepsin