NDNA3

NDNA3 (compound 14) is a selective inhibitor of Hsp90α (IC50: 0.51 μM). NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 (IC50: 12.66 μM) and MCF-10A (IC50: 11.72 μM) cells. NDNA3 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90α-dependent client proteins.

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  • Fòrmula: C28H32N2O3S
  • Peso molecular:476.63
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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