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Referencia número: HY-145233

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PfPKG-IN-1

PfPKG-IN-1 is a imidazole-based inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG).

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2866493-89-0
Fòrmula: C₂₄H₂₂ClN₇OS
Peso molecular:492.00

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

PfPKG-IN-1 Chemical Structure

No. CAS: 2866493-89-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

PfPKG-IN-1 is a imidazole-based inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG).

IC₅₀ & Target

Plasmodium

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Chemical Information

No. CAS 2866493-89-0
Peso molecular 492.00
Fòrmula C₂₄H₂₂ClN₇OS
SMILES

O=C(C1=NC=CS1)N(CC2)C[C@@H]2NC3=NC(N4C(C5=CC=CC(Cl)=C5)=NC(C6CC6)=C4)=CC=N3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yadav Bheemanaboina RR, et al. Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase. ACS Med. Chem. Lett. 2021 Nov 15.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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PfPKG-IN-1

Ver todos los productos específicos de isoformas Parasite

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Referencias

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PfPKG-IN-1 Related Classifications

HY-145233 Related Classifications