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Referencia número: HY-18252B

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(R)-Avanafil

(Synonyms: (R)-TA1790)

(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC₅₀: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1638497-26-3
Fòrmula: C₂₃H₂₆ClN₇O₃
Peso molecular:483.95

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(R)-Avanafil Chemical Structure

No. CAS: 1638497-26-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- IC₅₀ & Target
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Actividad biológica

Descripciòn

(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC₅₀: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction^[1].

IC₅₀ & Target

5.2 nM (PDE5)^[1].

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE) :

Chemical Information

No. CAS 1638497-26-3
Peso molecular 483.95
Fòrmula C₂₃H₂₆ClN₇O₃
SMILES

COC1=C(Cl)C=C(CNC2=C(C(NCC3=NC=CC=N3)=O)C=NC(N4[C@@H](CO)CCC4)=N2)C=C1
Synonyms

(R)-TA1790
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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(R)-Avanafil

High-Throughput Bioactive Compound Library

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

(R)-Avanafil Related Classifications

HY-18252B Related Classifications