TLR8 - toll like receptor 8 Gene

Species: Macaca fascicularis

Gene Type: protein coding
Gene ID: 102139990

About TLR8

Primary_assembly X: 11,558,668-11,575,637 forward strand.Macaca_fascicularis_6.0:CM021959.1

This gene has 1 transcript (splice variant), 199 orthologues and 21 paralogues.

TLR8 Products (2)

mRNA Protein Name
NM_001319618.1 NP_001306547.1 toll-like receptor 8 precursor
NM_001319618.1 NP_001306547.1 toll-like receptor 8 precursor

TLR8 Protein Structure

LRR_8

LRR_8: pfam13855 (64 - 136)

LRR_RI

LRR_RI: sd00033 (64 - 87)

LRR_RI

LRR_RI: sd00033 (99 - 125)

PPP1R42

PPP1R42: cl42388 (111 - 342)

LRR_RI

LRR_RI: sd00033 (126 - 146)

LRR_RI

LRR_RI: sd00033 (147 - 170)

LRR_RI

LRR_RI: sd00033 (171 - 201)

LRR_RI

LRR_RI: sd00033 (202 - 222)

LRR_RI

LRR_RI: sd00033 (223 - 246)

LRR_RI

LRR_RI: sd00033 (247 - 287)

PLN00113

PLN00113: cl33413 (281 - 747)

LRR_RI

LRR_RI: sd00033 (288 - 311)

LRR_RI

LRR_RI: sd00033 (338 - 367)

LRR_RI

LRR_RI: sd00033 (368 - 394)

LRR_RI

LRR_RI: sd00033 (395 - 418)

LRR_RI

LRR_RI: sd00033 (485 - 505)

LRR_RI

LRR_RI: sd00033 (506 - 530)

LRR_RI

LRR_RI: sd00033 (531 - 554)

LRR_RI

LRR_RI: sd00033 (555 - 584)

PPP1R42

PPP1R42: cl42388 (572 - 773)

LRR_RI

LRR_RI: sd00033 (585 - 639)

LRR_RI

LRR_RI: sd00033 (640 - 664)

LRR_RI

LRR_RI: sd00033 (665 - 688)

LRR_RI

LRR_RI: sd00033 (689 - 711)

LRR_RI

LRR_RI: sd00033 (713 - 736)

LRR_RI

LRR_RI: sd00033 (737 - 756)

PCC

PCC: cl28216 (741 - 828)

TIR

TIR: smart00255 (879 - 1021)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1040 a.a.
Protein Preferred Names Protein Names

toll-like receptor 8

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-13740 Resiquimod Agonist 99.95% Phase 2
HY-134581 Enpatoran Inhibitor 99.80% Phase 2
HY-13773 Motolimod Agonist 98.10% Phase 2
HY-109137 Selgantolimod Agonist 98.18% Phase 2
HY-134581A Enpatoran hydrochloride Inhibitor 99.42% Phase 2
HY-13740G Resiquimod (GMP) Agonist / Phase 2
HY-177617 Bazlitoran Agonist 95.30% Phase 2
HY-177617A Bazlitoran sodium Agonist 95.30% Phase 2
HY-109104 Telratolimod Agonist 98.85% Phase 1

Pre-clinical Phase

Bioactive Molecules (55)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128799 CL097 Agonist 99.90% Unkown
HY-160229 ssRNA40 sodium Activator 98.34% Unkown
HY-20457 TL8-506 Agonist 95.0% Unkown
HY-103697 Gardiquimod 99.91% Unkown
HY-103698 TLR7/8 agonist 1 Agonist 98.42% Unkown
HY-112667 CU-CPT-9a Antagonist 99.74% Unkown
HY-139323 TLR7/8-IN-1 Inhibitor 99.92% Unkown
HY-103698A TLR7/8 agonist 1 dihydrochloride Agonist 99.70% Unkown
HY-117066 CL075 Agonist 99.18% Unkown
HY-112050 CU-CPT-8m Antagonist 99.98% Unkown
HY-128799A CL097 hydrochloride Agonist 99.96% Unkown
HY-101929 CU-CPT17e Agonist 98.67% Unkown
HY-130797 TLR7/8 agonist 3 Agonist 99.96% Unkown
HY-153879 C12-TLRa Ligand 99.71% Unkown
HY-159102 PVP-037.2 Agonist 99.18% Unkown
HY-13740S Resiquimod-d5 Agonist 98.33% Unkown
HY-139017 TLR7/8 agonist 4 Agonist 99.18% Unkown
HY-131945 CU-115 Antagonist 99.63% Unkown
HY-138139B AXC-715 trihydrochloride Agonist 99.76% Unkown
HY-103697A Gardiquimod diTFA 99.0% Unkown
HY-138139A AXC-715 hydrochloride Agonist 99.89% Unkown
HY-112051 CU-CPT9b Antagonist 99.03% Unkown
HY-145885 TLR7/8 agonist 6 Agonist 98.93% Unkown
HY-176774 L07-2 Agonist 99.83% Unkown
HY-145960A MC-Val-Cit-PAB-Amide-TLR7 agonist 4 formic Agonist 97.70% Unkown
HY-164485 INI-4001 Activator / Unkown
HY-145960 MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Agonist 99.39% Unkown
HY-10018 Toll-like receptor modulator Modulator 99.36% Unkown
HY-178037 TLR9 antagonist 1 Antagonist / Unkown
HY-153543 TLR7/8 agonist 8 Agonist 98.69% Unkown
HY-139017A TLR7/8 agonist 4 TFA Agonist / Unkown
HY-141454 TLR8 agonist 2 Agonist / Unkown
HY-141454A TLR8 agonist 2 hydrochloride Agonist / Unkown
HY-169057 BI1543673 Inhibitor / Unkown
HY-153544 TLR7/8 agonist 9 Inhibitor / Unkown
HY-160228A ORN 02 sodium Activator / Unkown
HY-20457G TL8-506 (GMP) Agonist / Unkown
HY-159916 AYK004 Agonist / Unkown
HY-179209 TLR9-IN-2 Inhibitor / Unkown
HY-160228 ORN 02 Activator / Unkown
HY-179336 TLR7/8 agonist 14 Agonist / Unkown
HY-179047 SMU-L11-R Agonist / Unkown
HY-145886 TLR7/8 antagonist 1 Antagonist / Unkown
HY-175782 SMU-R39 Antagonist / Unkown
HY-183276 TLR8 antagonist-2 Antagonist / Unkown
HY-121496 3M-011 Agonist / Unkown
HY-161630 TLR8 agonist 8 Agonist / Unkown
HY-176553 KBD4466 Inhibitor / Unkown
HY-162845 TLR7/8 agonist 11 Agonist / Unkown
HY-161629 TLR8 agonist 7 Agonist / Unkown
HY-161631 TLR8 agonist 9 Agonist / Unkown
HY-163670 TLR7 agonist 21 Inhibitor / Unkown
HY-181841 TLR8 agonist 10 Agonist / Unkown
HY-159919 UM-3006 Agonist / Unkown
HY-177300 TLR7/8 agonist 13 Agonist / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992458 SBT8230 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TLR8 NCBI NCBI:51311