2. Gene
  3. EZH2 - enhancer of zeste 2 polycomb repressive complex 2 subunit Gene

EZH2 - enhancer of zeste 2 polycomb repressive complex 2 subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis

Also known as QtsA-18821

Gene ID: 102146280 | Gene type: protein coding

About EZH2

Primary_assembly 3: 176,294,482-176,428,804 reverse strand.Macaca_fascicularis_6.0:CM021941.1

This gene has 8 transcripts (splice variants), 237 orthologues and 17 paralogues.

EZH2 Products(10)

mRNA Protein Name
XM_045388191.1 XP_045244126.1 histone-lysine N-methyltransferase EZH2 isoform X2
XM_045388192.1 XP_045244127.1 histone-lysine N-methyltransferase EZH2 isoform X3
XM_045388195.1 XP_045244130.1 histone-lysine N-methyltransferase EZH2 isoform X6
XM_045388200.1 XP_045244135.1 histone-lysine N-methyltransferase EZH2 isoform X10
XM_045388194.1 XP_045244129.1 histone-lysine N-methyltransferase EZH2 isoform X5
XM_045388198.1 XP_045244133.1 histone-lysine N-methyltransferase EZH2 isoform X9
XM_045388190.1 XP_045244125.1 histone-lysine N-methyltransferase EZH2 isoform X1
XM_045388193.1 XP_045244128.1 histone-lysine N-methyltransferase EZH2 isoform X4
XM_045388197.1 XP_045244132.1 histone-lysine N-methyltransferase EZH2 isoform X8
XM_045388196.1 XP_045244131.1 histone-lysine N-methyltransferase EZH2 isoform X7
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EZH2

Histone-lysine N-methyltransferase EZH2

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13803 Tazemetostat Inhibitor 99.93% Yes
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-145602 Tulmimetostat Inhibitor 99.79% Phase 2
HY-13470 GSK126 Inhibitor 99.98% Phase 1
Pre-clinical Phase
Bioactive Molecules (72)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13500 GSK343 Inhibitor 99.85% Unkown
HY-10442 3-Deazaneplanocin A Inhibitor 99.97% Unkown
HY-12186 3-Deazaneplanocin A hydrochloride Inhibitor 99.98% Unkown
HY-15646 UNC1999 Inhibitor 99.87% Unkown
HY-133129 MS1943 Inhibitor 98.92% Unkown
HY-148333 MS177 Inhibitor 99.55% Unkown
HY-101512 A-395 Inhibitor 99.12% Unkown
HY-147525 PROTAC EZH2 Degrader-1 Inhibitor 99.44% Unkown
HY-162250 MS8847 Inhibitor 99.78% Unkown
HY-103682 PF-06726304 Inhibitor 99.71% Unkown
HY-16986 EPZ011989 Inhibitor 98.79% Unkown
HY-N5024 Gambogenic acid Inhibitor 99.91% Unkown
HY-141877 MS4322 Degrader 99.14% Unkown
HY-15555 EPZ005687 Inhibitor 99.46% Unkown
HY-157844 NUCC-0226272 Degrader 99.68% Unkown
HY-78694 5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide Ligand 98.22% Unkown
HY-100846 JQEZ5 Inhibitor 98.14% Unkown
HY-12856 GSK503 Inhibitor 99.52% Unkown
HY-157164 PROTAC EZH2 Degrader-2 Degrader 98.77% Unkown
HY-15573 EI1 Inhibitor 98.84% Unkown
HY-147090 Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH Degrader 99.06% Unkown
HY-162384 EPIC-0628 Inhibitor 98.93% Unkown
HY-144330 TDI-6118 Inhibitor 99.08% Unkown
HY-141877B MS4322 (isomer) 99.87% Unkown
HY-A0298 EZH2-IN-2 Inhibitor 98.51% Unkown
HY-147230 EZH2-IN-13 Inhibitor 99.72% Unkown
HY-101508 GNA002 Inhibitor 98.02% Unkown
HY-131246 DM-01 Inhibitor 98.05% Unkown
HY-146999 YM458 Inhibitor 99.16% Unkown
HY-176165 CDK9/EZH2-IN-1 Inhibitor 99.08% Unkown
HY-119198 NSC745885 Inhibitor 98.0% Unkown
HY-111418 EBI-2511 Inhibitor 98.67% Unkown
HY-136188 UNC2399 Inhibitor 99.16% Unkown
HY-16986A EPZ011989 trifluoroacetate Inhibitor 98.71% Unkown
HY-144881 (S)-HH2853 Inhibitor / Unkown
HY-144882 (R)-HH2853 Inhibitor / Unkown
HY-122936 Tanshindiol C Inhibitor 98.47% Unkown
HY-134899 CPI-1328 Inhibitor / Unkown
HY-12186G 3-Deazaneplanocin A hydrochloride (GMP) Inhibitor / Unkown
HY-103682A PF-06726304 acetate Inhibitor / Unkown
HY-185582 EZH2 ligand-4 / Unkown
HY-181410 PROTAC EZH2 Degrader-41 / Unkown
HY-156292 IHMT-EZH2-426 Inhibitor / Unkown
HY-179351 EZH2 ligand-1 Ligand / Unkown
HY-181319 PROTAC EZH2 Degrader-21 Degrader / Unkown
HY-149463 EZH2-IN-16 Inhibitor / Unkown
HY-163288 EZH2/HSP90-IN-29 Inhibitor / Unkown
HY-177497 SKLB-03220 Inhibitor / Unkown
HY-181157 T/E PPI-IN-1 Inhibitor / Unkown
HY-179386 PARP1/EZH2-IN-1 Inhibitor / Unkown
HY-141566 EZH2-IN-5 Inhibitor / Unkown
HY-181327 PROTAC EZH2 Degrader-26 Degrader / Unkown
HY-143616 EZH2-IN-7 Inhibitor / Unkown
HY-179499 PROTAC EZH2 Degrader-9 Degrader / Unkown
HY-160423 MS8815N Control / Unkown
HY-122640 NPD13668 Inhibitor / Unkown
HY-132885 PARP/EZH2-IN-1 Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-181331 PROTAC EZH2 Degrader-27 Inhibitor / Unkown
HY-181333 PROTAC EZH2 Degrader-38 Degrader / Unkown
HY-162601 D-01 Inhibitor / Unkown
HY-178694 DC-PRC2in-01 Inhibitor / Unkown
HY-179500 EZH2 ligand-Linker Conjugate 1 / Unkown
HY-161083 PARP/EZH2-IN-2 Inhibitor / Unkown
HY-139150 EZH2-IN-4 Inhibitor / Unkown
HY-181413 PROTAC EZH2 Degrader-44 Degrader / Unkown
HY-163741 EZH2-IN-19 Inhibitor / Unkown
HY-154854 BBDDL2059 Inhibitor / Unkown
HY-181393 EZH2 ligand-3 Ligand / Unkown
HY-169958 EZH2-IN-22 Inhibitor / Unkown
HY-116605 GSK926 Inhibitor / Unkown
HY-122115 DCE_42 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EZH2 NCBI NCBI:2146