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Cat. No.: HY-185582

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EZH2 ligand-4

EZH2 ligand-4 (Precursor 1) is a ligand for the target protein for PROTAC (EZH2). EZH2 ligand-4 can be used to synthesize MS8847 (HY-162250).

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CAS No.: 3050872-19-7
Formule: C₃₇H₄₉N₅O₅
Masse moléculaire:643.82

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Please store the product under the recommended conditions in the Certificate of Analysis.

EZH2 ligand-4 Chemical Structure

CAS No.: 3050872-19-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

EZH2 ligand-4 (Precursor 1) is a ligand for the target protein for PROTAC (EZH2). EZH2 ligand-4 can be used to synthesize MS8847 (HY-162250)^[1].

IC₅₀ & Target^[1]

EZH2

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Chemical Information

CAS No. 3050872-19-7
Masse moléculaire 643.82
Formule C₃₇H₄₉N₅O₅
SMILES

O=C(CCN1CCN(CC1)CC2=CC=C(C3=CC(N(C4CCOCC4)CC)=C(C)C(C(NCC5=C(C=C(NC5=O)C)C)=O)=C3)C=C2)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Velez J, et al. Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2. Eur J Med Chem. 2024;267:116154. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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EZH2 ligand-4

Voir tous les produits spécifiques à Isoform Histone Methyltransferase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EZH2 ligand-4 Related Classifications

HY-185582 Related Classifications