MS8815N
MS8815N is a negative control of EZH2 PROTAC degrader MS8815 (HY-148334). MS8815N is incapable of recruiting the VHL E3 ligase but retains the same EZH2 binding moiety and linker. MS8815N can be used for triple-negative breast cancer (TNBC) research.
(Pink: EZH2 ligand (HY-147230); Blue: Ligands for E3 Ligase E3 ligase ligand; Black: linker (HY-B0704)).
For research use only. We do not sell to patients.
- CAS No.: 2855085-26-4
- Formula: C72H93N9O8S
- Molecular Weight:1244.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EZH2 |
Chemical Information
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CAS No. 2855085-26-4
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Molecular Weight 1244.63
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Formula C72H93N9O8S
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SMILES
CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(CCCCCCCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@H](C5)OCC6=CC=CC=C6)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)=O)=CC(C(NCC9=C(C=C(NC9=O)C)C)=O)=C2C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)