2. Gene
  3. Rad51 - RAD51 recombinase Gene

Rad51 - RAD51 recombinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Reca; Rad51a

Gene ID: 19361 | Gene type: protein coding

About Rad51

Chromosome 2: 118,943,274-118,977,926 forward strand.GRCm39:CM000995.3

This gene has 8 transcripts (splice variants), 220 orthologues, 6 paralogues and is associated with 11 phenotypes. Biased expression in placenta adult (RPKM 14.2), liver E14 (RPKM 13.5) and 13 other tissues.

Summary

Enables chromatin binding activity and single-stranded DNA binding activity. Involved in telomere maintenance via recombination and telomere maintenance via telomere lengthening. Acts upstream of or within several processes, including DNA metabolic process; cellular response to hydroxyurea; and chromosome organization. Located in chromosome, telomeric region; cytoplasm; and lateral element. Is expressed in several structures, including brain; compacted morula; gonad; hemolymphoid system; and paravertebral ganglion. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; congenital mirror movement disorder; and ovarian Cancer. Orthologous to human RAD51 (RAD51 recombinase). [provided by Alliance of Genome Resources, Apr 2022]

Rad51 Products(1)

mRNA Protein Name
NM_011234.5 NP_035364.1 DNA repair protein RAD51 homolog 1

Rad51 Protein Structure

recomb_RAD51

recomb_RAD51: TIGR02239 (24 - 338)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

DNA repair protein RAD51 homolog 1

RAD51 homolog A

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-19793 RS-1 Activator 98.95% Phase 2
HY-10206 Amuvatinib Inhibitor 99.47% Phase 2
HY-10206A Amuvatinib hydrochloride Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0086 DIDS sodium salt Inhibitor 99.13% Unkown
HY-101462 RAD51 Inhibitor B02 Inhibitor 99.91% Unkown
HY-15317 RI-1 Inhibitor 99.83% Unkown
HY-103710 IBR2 Inhibitor 98.34% Unkown
HY-126020 Bractoppin Inhibitor 99.70% Unkown
HY-150147 CAM833 Inhibitor 99.79% Unkown
HY-122705 RAD51-IN-1 Inhibitor 99.89% Unkown
HY-148183 Homologous recombination-IN-1 Inhibitor 99.65% Unkown
HY-16904 RI-2 Inhibitor 99.64% Unkown
HY-111887 Emzadirib Inhibitor 99.79% Unkown
HY-126972A RI(dl)-2 TFA Inhibitor 98.02% Unkown
HY-136604 RAD51-IN-3 Inhibitor 99.24% Unkown
HY-143736 RAD51-IN-5 Inhibitor 98.87% Unkown
HY-143735 RAD51-IN-4 Inhibitor / Unkown
HY-143741 RAD51-IN-7 Inhibitor / Unkown
HY-143737 RAD51-IN-6 Inhibitor / Unkown
HY-150958 RAD51-IN-8 / Unkown
HY-121693 DIDS Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rad51 NCBI NCBI:5888