Son - Son DNA binding protein Gene

Also Known as nrebp; mKIAA1019; 2900011L12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20658

Summary

Enables RS domain binding activity. Predicted to be involved in several processes, including mRNA processing; mitotic cytokinesis; and regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing. Predicted to be located in nuclear speck. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human SON (SON DNA and RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Son Products (2)

mRNA Protein Name
NM_019973.2 NP_064357.2 protein SON isoform 2
NM_178880.4 NP_849211.3 protein SON isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables RS domain binding IPI
IPI: Inferred from physical interaction
15798186 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9185665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein SON

  • NRE-binding protein

  • Son cell proliferation protein

  • negative regulatory element-binding protein

Son Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Son Q9QX47 RUNX1T1 Homo sapiens Q06455
Anti Tag CoIP
18952841
Cross
Son Q9QX47 RUNX1T1 Homo sapiens Q06455
Pull Down
18952841
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-125817 BI-3406 Inhibitor 99.95% Unkown
HY-114398 BAY-293 Inhibitor 98.97% Unkown
HY-18674 K-Ras-IN-1 Inhibitor 98.00% Unkown
HY-132966 ASP2453 Inhibitor 98.28% Unkown
HY-124755 RAS activator compound 1 Activator 98.90% Unkown
HY-144965 SOS1-IN-12 Inhibitor / Unkown
HY-144967 SOS1-IN-13 Inhibitor / Unkown
HY-145046 SOS1-IN-3 Inhibitor / Unkown
HY-159888 SON38 Inhibitor / Unkown
HY-161654 PROTAC SOS1 degrader-10 / Unkown
HY-168480 SOS2 ligand 1 Ligand / Unkown
HY-168514 SOS1/EGFR-IN-2 Inhibitor / Unkown
HY-172221 SOS1-IN-18 Inhibitor / Unkown
HY-175326 SOS1-IN-21 Inhibitor / Unkown
HY-175560 SOS1-IN-22 Inhibitor / Unkown
HY-176170 SOS1-IN-19 Inhibitor / Unkown
HY-RS13566 SON Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-161655 SOS1 Ligand intermediate-5 Inhibitor / Unkown
HY-RS18222 Son Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24699 Son Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Son NCBI NCBI:6651