1. GPCR/G Protein
  2. Ras
  3. K-Ras-IN-1

K-Ras-IN-1 

Cat. No.: HY-18674 Purity: 98.13%
Handling Instructions

K-Ras-IN-1 is a K-Ras inhibitor. K-Ras-IN-1 K-Ras (G12V) binds to K-Ras (WT), K-Ras (G12D), K-Ras (G12V), and H-Ras. K-Ras-IN-1 has potential for the research of pancreatic, colon and lung carcinomas.

For research use only. We do not sell to patients.

K-Ras-IN-1 Chemical Structure

K-Ras-IN-1 Chemical Structure

CAS No. : 84783-01-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 462 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

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Description

K-Ras-IN-1 is a K-Ras inhibitor. K-Ras-IN-1 K-Ras (G12V) binds to K-Ras (WT), K-Ras (G12D), K-Ras (G12V), and H-Ras. K-Ras-IN-1 has potential for the research of pancreatic, colon and lung carcinomas[1][2].

IC50 & Target

K-Ras[1]

Molecular Weight

207.29

Formula

C₁₁H₁₃NOS

CAS No.

84783-01-7

SMILES

S=C(C1=CC=CC=C1O)N2CCCC2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (482.42 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8242 mL 24.1208 mL 48.2416 mL
5 mM 0.9648 mL 4.8242 mL 9.6483 mL
10 mM 0.4824 mL 2.4121 mL 4.8242 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (12.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (12.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (12.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

K-Ras-IN-1RasK-RaspancreaticcolonlungcarcinomasmutationsInhibitorinhibitorinhibit

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Product Name:
K-Ras-IN-1
Cat. No.:
HY-18674
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