CDK5 - cyclin dependent kinase 5 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 281066

About CDK5

Primary_assembly 4: 113,630,176-113,634,606 reverse strand.ARS-UCD1.2:CM008171.2

This gene has 1 transcript (splice variant), 170 orthologues and 27 paralogues.

CDK5 Products (1)

mRNA Protein Name
NM_174017.2 NP_776442.1 cyclin-dependent kinase 5

CDK5 Protein Structure

STKc_CDK5

STKc_CDK5: cd07839 (2 - 285)

  • 0
  • 100
  • 200
  • 292 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 5

  • PDPK

  • TPKII catalytic subunit

  • cell division protein kinase 5

  • cyclin-dependent-like kinase 5

  • proline-directed protein kinase 33 kDa subunit

  • serine/threonine-protein kinase PSSALRE

  • tau protein kinase II catalytic subunit

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16297A Abemaciclib Inhibitor 99.97% Yes
HY-10492 Dinaciclib Inhibitor 99.80% Yes
HY-16297 Abemaciclib methanesulfonate Inhibitor 99.95% Yes

Clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Phase
HY-10580 GSK 3 Inhibitor IX Inhibitor 99.73% Phase 4
HY-112272A Lerociclib dihydrochloride Inhibitor 98.51% Phase 3
HY-112272 Lerociclib Inhibitor 96.42% Phase 3
HY-30237 (R)-Roscovitine Inhibitor 99.53% Phase 2
HY-103712A Samuraciclib hydrochloride Inhibitor 99.98% Phase 2
HY-X0009 Tambiciclib Inhibitor 99.68% Phase 2
HY-50940 AT7519 Inhibitor 99.69% Phase 2
HY-137478 KB-0742 Inhibitor 99.63% Phase 2
HY-137478A KB-0742 dihydrochloride Inhibitor 98.77% Phase 2
HY-103712 Samuraciclib Inhibitor 99.55% Phase 2
HY-103712B Samuraciclib hydrochloride dihydrate Inhibitor 99.90% Phase 2
HY-50943 AT7519 Hydrochloride Inhibitor 99.16% Phase 2
HY-103712C Samuraciclib hydrochloride hydrate Inhibitor 99.88% Phase 2
HY-50940A AT7519 TFA Inhibitor 99.75% Phase 2
HY-X0009A Tambiciclib dimaleate Inhibitor 99.53% Phase 2
HY-10012 AZD-5438 Inhibitor 99.91% Phase 1
HY-10014 R547 Inhibitor 99.57% Phase 1
HY-11001 PHA-793887 Inhibitor 99.25% Phase 1
HY-12871B Atuveciclib Inhibitor 99.75% Phase 1
HY-15504 RGB-286638 Inhibitor 99.67% Phase 1
HY-15504A RGB-286638 free base Inhibitor 98.09% Phase 1

Pre-clinical Phase

Bioactive Molecules (69)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12302 Kenpaullone Inhibitor 98.20% Unkown
HY-15154 NG 52 Inhibitor 99.88% Unkown
HY-18340 (R)​-​CR8 Inhibitor 99.52% Unkown
HY-18299A Purvalanol A Inhibitor 98.61% Unkown
HY-108359 Alsterpaullone Inhibitor 99.85% Unkown
HY-144117 GFB-12811 Inhibitor 98.04% Unkown
HY-11009 CGP60474 Inhibitor 98.90% Unkown
HY-13461A PHA-767491 hydrochloride Inhibitor 99.49% Unkown
HY-103221 MeBIO Inhibitor 98.0% Unkown
HY-18340A (R)-CR8 trihydrochloride Inhibitor 99.37% Unkown
HY-13461 PHA-767491 Inhibitor 99.97% Unkown
HY-X0150 JSH-150 Inhibitor 98.36% Unkown
HY-18299 Purvalanol B Inhibitor 97.0% Unkown
HY-123772 CDK5 inhibitor 20-223 Inhibitor 99.62% Unkown
HY-12280 THZ2 Inhibitor 99.03% Unkown
HY-112358 GW8510 Inhibitor 99.04% Unkown
HY-13266A BS-181 hydrochloride Inhibitor 99.93% Unkown
HY-119940 MC180295 Inhibitor 98.07% Unkown
HY-145694 CDK5-IN-3 Inhibitor 99.49% Unkown
HY-151071 TMX-3013 Inhibitor 98.02% Unkown
HY-W011428 Olomoucine Inhibitor 99.88% Unkown
HY-112403 (S)-Roscovitine Inhibitor 99.15% Unkown
HY-155218 TMX-2172 Degrader 99.38% Unkown
HY-117025A Manzamine A hydrochloride Inhibitor 99.66% Unkown
HY-151069 TMX-2039 Inhibitor 99.42% Unkown
HY-121035 7BIO Inhibitor 99.20% Unkown
HY-107419 NU6140 Inhibitor 99.53% Unkown
HY-137342 SB1-G-187 Degrader 98.70% Unkown
HY-154851 GSK-3 inhibitor 3 Inhibitor 99.10% Unkown
HY-14372 BS-194 Inhibitor 99.13% Unkown
HY-P10440 Cdk5i peptide Inhibitor 98.93% Unkown
HY-123045 PNU-292137 Inhibitor 99.95% Unkown
HY-139725 CDK5-IN-1 Inhibitor 98.47% Unkown
HY-136726 CGP-82996 Inhibitor 98.12% Unkown
HY-111930 5-Iodo-indirubin-3'-monoxime Inhibitor 98.12% Unkown
HY-119715 AG-012986 Inhibitor 99.78% Unkown
HY-15241 NVP-LCQ195 Inhibitor 98.88% Unkown
HY-13266 BS-181 Inhibitor 98.10% Unkown
HY-103381 NSC693868 Inhibitor 99.0% Unkown
HY-154852 GSK-3 inhibitor 4 Inhibitor 99.02% Unkown
HY-114903 (E/Z)-BIO-acetoxime Inhibitor 99.9% Unkown
HY-103383 (R)-DRF053 dihydrochloride Inhibitor 99.30% Unkown
HY-112468 PNU112455A hydrochloride Inhibitor 99.56% Unkown
HY-117025 Manzamine A Inhibitor 98.2% Unkown
HY-164906 TMX-2138 Degrader / Unkown
HY-142696 CDK6/PIM1-IN-1 Inhibitor / Unkown
HY-N12625 (R)-(+)-O-Demethylbuchenavianine Inhibitor 98.67% Unkown
HY-151407 CDK1-IN-3 Inhibitor / Unkown
HY-151409 CDK1-IN-5 Inhibitor / Unkown
HY-110368 BS-181 dihydrochloride Inhibitor / Unkown
HY-112363 Aloisine A Inhibitor / Unkown
HY-182986 LS-Q2 Inhibitor / Unkown
HY-111931 Indirubin-3'-monoxime-5-sulphonic acid Inhibitor / Unkown
HY-163856 CDK7-IN-30 Inhibitor / Unkown
HY-151878 CDK7-IN-20 Inhibitor / Unkown
HY-178142 Multi-kinase-IN-7 Inhibitor / Unkown
HY-161595 CDK5-IN-4 Inhibitor / Unkown
HY-111932 Indirubin-5-sulfonate Inhibitor / Unkown
HY-183280 17β-HSD10/CDK5-IN-1 Inhibitor / Unkown
HY-137478B KB-0742 hydrochloride Inhibitor / Unkown
HY-150641 CDK-IN-9 Inhibitor / Unkown
HY-161463 CDK2-IN-28 Inhibitor / Unkown
HY-145693 CDK5-IN-2 Inhibitor / Unkown
HY-151408 CDK1-IN-4 Inhibitor / Unkown
HY-173348 BLINK15 Inhibitor / Unkown
HY-182028 17β-HSD10-IN-4 / Unkown
HY-112336 Aloisine RP106 Inhibitor / Unkown
HY-173347 BLINK11 Inhibitor / Unkown
HY-182470 AG-012986 dihydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CDK5 NCBI NCBI:1020