Aloisine RP106
Based on 1 Customer Validation
Aloisine RP106 (compound 38) is a potent inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 with IC50s of 0.70µM, 1.5µM, 0.92 µM, respectively.
For research use only. We do not sell to patients.
- Purity : 99.76%
- CAS No.: 496864-15-4
- Formula: C17H19N3O
- Molecular Weight:281.35
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Cdk1/cyclin B 0.7 μM (IC50) |
Cdk5/p25 1.5 μM (IC50) |
GSK-3 0.92 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
0.92 μM
Compound: 38
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Inhibition of glycogen synthase kinase-3 beta, purified from porcine brain or expressed in and purified from insect Sf9 cells
Inhibition of glycogen synthase kinase-3 beta, purified from porcine brain or expressed in and purified from insect Sf9 cells
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[PMID: 12519061] |
Chemical Information
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CAS No. 496864-15-4
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Appearance Solid
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Molecular Weight 281.35
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Formula C17H19N3O
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Color White to off-white
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SMILES
COC1=CC=C(C2=C(CCCC)C3=NC=CN=C3N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aloisine RP106 Related Classifications
HY-112336 Related Classifications
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