Aloisine RP106
Aloisine RP106 (compound 38) is a potent inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 with IC50s of 0.70µM, 1.5µM, 0.92 µM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 496864-15-4
- Formula: C17H19N3O
- Molecular Weight:281.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cdk1/cyclin B 0.7 μM (IC50) |
Cdk5/p25 1.5 μM (IC50) |
GSK-3 0.92 μM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
0.92 μM
Compound: 38
|
Inhibition of glycogen synthase kinase-3 beta, purified from porcine brain or expressed in and purified from insect Sf9 cells
Inhibition of glycogen synthase kinase-3 beta, purified from porcine brain or expressed in and purified from insect Sf9 cells
|
[PMID: 12519061] |
Chemical Information
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CAS No. 496864-15-4
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Molecular Weight 281.35
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Formula C17H19N3O
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SMILES
COC1=CC=C(C2=C(CCCC)C3=NC=CN=C3N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)