TLR8 - toll like receptor 8 Gene

Sus scrofa

Also known as TLR7

Gene ID: 397384 | Gene type: protein coding

About TLR8

Primary_assembly X: 9,597,604-9,616,757 forward strand.Sscrofa11.1:CM000830.5

This gene has 6 transcripts (splice variants), 199 orthologues and 23 paralogues. Biased expression in spleen (RPKM 29.8), lung (RPKM 8.2) and 1 other tissue.

TLR8 Products(1)

mRNA	Protein	Name
NM_214187.1	NP_999352.1	toll-like receptor 8 precursor

TLR8 Protein Structure

LRR_8

LRR_RI

PLN00113

LRR_RI

PPP1R42

LRR_RI

LRRCT

TIR

0
200
400
600
800
1000
1107 a.a.

Protein Preferred Names

Protein Names

toll-like receptor 8

Toll-like receptor 7

Related Agents

Clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13740	Resiquimod	Agonist	99.95%	Phase 2
HY-134581	Enpatoran	Inhibitor	99.80%	Phase 2
HY-13773	Motolimod	Agonist	98.10%	Phase 2
HY-109137	Selgantolimod	Agonist	98.18%	Phase 2
HY-134581A	Enpatoran hydrochloride	Inhibitor	99.42%	Phase 2
HY-13740G	Resiquimod (GMP)	Agonist	/	Phase 2
HY-177617	Bazlitoran	Agonist	/	Phase 2
HY-177617A	Bazlitoran sodium	Agonist	/	Phase 2
HY-109104	Telratolimod	Agonist	98.85%	Phase 1

Pre-clinical Phase

Bioactive Molecules (55)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-128799	CL097	Agonist	99.90%	Unkown
HY-160229	ssRNA40 sodium	Activator	98.34%	Unkown
HY-103697	Gardiquimod		99.91%	Unkown
HY-20457	TL8-506	Agonist	95.0%	Unkown
HY-103698	TLR7/8 agonist 1	Agonist	98.42%	Unkown
HY-112667	CU-CPT-9a	Antagonist	99.74%	Unkown
HY-139323	TLR7/8-IN-1	Inhibitor	99.92%	Unkown
HY-103698A	TLR7/8 agonist 1 dihydrochloride	Agonist	99.70%	Unkown
HY-117066	CL075	Agonist	99.18%	Unkown
HY-112050	CU-CPT-8m	Antagonist	99.98%	Unkown
HY-128799A	CL097 hydrochloride	Agonist	99.96%	Unkown
HY-101929	CU-CPT17e	Agonist	98.67%	Unkown
HY-130797	TLR7/8 agonist 3	Agonist	99.96%	Unkown
HY-153879	C12-TLRa	Ligand	99.0%	Unkown
HY-159102	PVP-037.2	Agonist	99.18%	Unkown
HY-139017	TLR7/8 agonist 4	Agonist	99.18%	Unkown
HY-131945	CU-115	Antagonist	99.63%	Unkown
HY-13740S	Resiquimod-d5	Agonist	98.33%	Unkown
HY-112051	CU-CPT9b	Antagonist	99.03%	Unkown
HY-138139B	AXC-715 trihydrochloride	Agonist	99.76%	Unkown
HY-103697A	Gardiquimod diTFA		99.0%	Unkown
HY-138139A	AXC-715 hydrochloride	Agonist	99.89%	Unkown
HY-145885	TLR7/8 agonist 6	Agonist	98.93%	Unkown
HY-176774	L07-2	Agonist	99.83%	Unkown
HY-145960A	MC-Val-Cit-PAB-Amide-TLR7 agonist 4 formic	Agonist	97.70%	Unkown
HY-164485	INI-4001	Activator	/	Unkown
HY-145960	MC-Val-Cit-PAB-Amide-TLR7 agonist 4	Agonist	99.39%	Unkown
HY-10018	Toll-like receptor modulator	Modulator	99.36%	Unkown
HY-178037	TLR9 antagonist 1	Antagonist	/	Unkown
HY-153543	TLR7/8 agonist 8	Agonist	98.69%	Unkown
HY-139017A	TLR7/8 agonist 4 TFA	Agonist	/	Unkown
HY-141454	TLR8 agonist 2	Agonist	/	Unkown
HY-141454A	TLR8 agonist 2 hydrochloride	Agonist	/	Unkown
HY-169057	BI1543673	Inhibitor	/	Unkown
HY-153544	TLR7/8 agonist 9	Inhibitor	/	Unkown
HY-160228A	ORN 02 sodium	Activator	/	Unkown
HY-20457G	TL8-506 (GMP)	Agonist	/	Unkown
HY-179209	TLR9-IN-2	Inhibitor	/	Unkown
HY-160228	ORN 02	Activator	/	Unkown
HY-179336	TLR7/8 agonist 14	Agonist	/	Unkown
HY-179047	SMU-L11-R	Agonist	/	Unkown
HY-145886	TLR7/8 antagonist 1	Antagonist	/	Unkown
HY-175782	SMU-R39	Antagonist	/	Unkown
HY-183276	TLR8 antagonist-2	Antagonist	/	Unkown
HY-121496	3M-011	Agonist	/	Unkown
HY-161630	TLR8 agonist 8	Agonist	/	Unkown
HY-176553	KBD4466	Inhibitor	/	Unkown
HY-162845	TLR7/8 agonist 11	Agonist	/	Unkown
HY-161629	TLR8 agonist 7	Agonist	/	Unkown
HY-161631	TLR8 agonist 9	Agonist	/	Unkown
HY-163670	TLR7 agonist 21	Inhibitor	/	Unkown
HY-159916	AYK004	Agonist	/	Unkown
HY-181841	TLR8 agonist 10	Agonist	/	Unkown
HY-159919	UM-3006	Agonist	/	Unkown
HY-177300	TLR7/8 agonist 13	Agonist	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P992458	SBT8230	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	TLR8	NCBI	NCBI:51311

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