2. Gene
  3. CDK8 - cyclin dependent kinase 8 Gene

CDK8 - cyclin dependent kinase 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 486035 | Gene type: protein coding

About CDK8

Primary_assembly 25: 13,180,701-13,315,567 reverse strand.ROS_Cfam_1.0:CM025124.1

This gene has 3 transcripts (splice variants), 217 orthologues and 25 paralogues.

CDK8 Products(5)

mRNA Protein Name
XM_038435006.1 XP_038290934.1 cyclin-dependent kinase 8 isoform X1
XM_038435007.1 XP_038290935.1 cyclin-dependent kinase 8 isoform X2
XM_038435008.1 XP_038290936.1 cyclin-dependent kinase 8 isoform X3
XM_038435010.1 XP_038290938.1 cyclin-dependent kinase 8 isoform X5
XM_038435009.1 XP_038290937.1 cyclin-dependent kinase 8 isoform X4

CDK8 Protein Structure

STKc_CDK8

STKc_CDK8: cd07868 (2 - 334)

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  • 464 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 8

Related Agents

Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-X0009 Tambiciclib Inhibitor 99.21% Phase 2
HY-137478 KB-0742 Inhibitor 99.63% Phase 2
HY-137478A KB-0742 dihydrochloride Inhibitor 98.77% Phase 2
HY-X0009A Tambiciclib dimaleate Inhibitor 99.53% Phase 2
HY-101800 Senexin B Inhibitor 99.09% Phase 1
HY-111388B Romaciclib hydrochloride Inhibitor 99.98% Phase 1
Pre-clinical Phase
Bioactive Molecules (44)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0400 Wogonin Inhibitor 99.83% Unkown
HY-120350 BI-1347 Inhibitor 99.85% Unkown
HY-126675A AS2863619 Inhibitor 98.02% Unkown
HY-111388A Romaciclib monohydrochloride Inhibitor 99.29% Unkown
HY-101611 MSC2530818 Inhibitor 99.62% Unkown
HY-15681 Senexin A Inhibitor 99.58% Unkown
HY-19984 CCT-251921 Inhibitor 99.12% Unkown
HY-122586 BRD6989 Inhibitor 99.54% Unkown
HY-12280 THZ2 Inhibitor 99.03% Unkown
HY-145121 DS96432529 Inhibitor 99.93% Unkown
HY-111518 JH-XI-10-02 Inhibitor 99.73% Unkown
HY-149209 LL-K8-22 Degrader 99.06% Unkown
HY-126675 AS2863619 free base Inhibitor 99.87% Unkown
HY-139875 JH-XVI-178 Inhibitor 98.87% Unkown
HY-12293 LY2857785 Inhibitor 99.21% Unkown
HY-143889 Senexin C Inhibitor 99.19% Unkown
HY-149974 CDK8-IN-13 Inhibitor 99.14% Unkown
HY-168683 CDK8 ligand 1 Degrader 99.88% Unkown
HY-151463 CDK8-IN-11 Inhibitor 98.18% Unkown
HY-111427 CDK8/19-IN-1 Inhibitor 98.08% Unkown
HY-111388 SEL120-34A Inhibitor 99.49% Unkown
HY-103492 CDK8-IN-1 Inhibitor 98.62% Unkown
HY-170813 P162-0948 Inhibitor / Unkown
HY-148561 CDK8-IN-12 Inhibitor 99.74% Unkown
HY-125001 JH-VIII-49 Inhibitor / Unkown
HY-15681A Senexin A hydrochloride Inhibitor / Unkown
HY-168846 CDK8/19-IN-3 Inhibitor / Unkown
HY-151371 CDK8-IN-10 Inhibitor / Unkown
HY-158377 CDK8/19-IN-2 Inhibitor / Unkown
HY-147716 CDK8-IN-6 Inhibitor / Unkown
HY-137478B KB-0742 hydrochloride Inhibitor / Unkown
HY-162600 CDK8-IN-15 Inhibitor / Unkown
HY-183074 RO8323 Inhibitor / Unkown
HY-176281 PI3Kα-IN-26 Inhibitor / Unkown
HY-169633 CDK8-IN-17 Inhibitor / Unkown
HY-169541 CDK8-IN-18 Inhibitor / Unkown
HY-176282 CDK8-IN-19 Inhibitor / Unkown
HY-182986 LS-Q2 Inhibitor / Unkown
HY-114178 CDK8-IN-2 Inhibitor / Unkown
HY-180124 CDK8-IN-20 Inhibitor / Unkown
HY-N0400R Wogonin (Standard) Inhibitor / Unkown
HY-147527 CDK8-IN-5 Inhibitor / Unkown
HY-147717 CDK8-IN-7 Inhibitor / Unkown
HY-171174 CDK8-IN-16 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CDK8 NCBI NCBI:1024