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Cat. No.: HY-169633

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CDK8-IN-17

Name: CDK8-IN-17
Brand: MedChemExpress
SKU: HY-169633
Price: 110.00 USD
Availability: InStock
Rating: 5 (1 reviews)

CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC₅₀ value of 9 nM, which can be used in cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 451458-32-5
Formule: C₂₁H₂₀N₄OS
Masse moléculaire:376.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

CDK8-IN-17 Chemical Structure

CAS No.: 451458-32-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC₅₀ value of 9 nM, which can be used in cancer research^[1].

IC₅₀ & Target

^[1]

CDK8

9 nM (IC₅₀)

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Chemical Information

CAS No. 451458-32-5
Masse moléculaire 376.47
Formule C₂₁H₂₀N₄OS
SMILES

O=C1C2=C(N=C(N1C3=CC=C(CC)C=C3)SCC4=C(C)C=CC=C4)NN=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang T, et al. Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening[J]. European journal of medicinal chemistry, 2017, 129: 275-286. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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CDK8-IN-17

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Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

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Help & FAQs

CDK8-IN-17 Related Classifications

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