2. Gene
  3. CGAS - cyclic GMP-AMP synthase Gene

CGAS - cyclic GMP-AMP synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)

Also known as MB21D1

Gene ID: 611033 | Gene type: protein coding

About CGAS

Primary_assembly 12: 36,066,172-36,085,743 reverse strand.ROS_Cfam_1.0:CM025111.1

This gene has 1 transcript (splice variant), 185 orthologues and 7 paralogues.

CGAS Products(6)

mRNA Protein Name
XM_038683963.1 XP_038539891.1 cyclic GMP-AMP synthase isoform X5
XM_038683960.1 XP_038539888.1 cyclic GMP-AMP synthase isoform X2
XM_038683959.1 XP_038539887.1 cyclic GMP-AMP synthase isoform X1
XM_038683961.1 XP_038539889.1 cyclic GMP-AMP synthase isoform X3
XM_038683958.1 XP_038539886.1 cyclic GMP-AMP synthase isoform X6
XM_038683962.1 XP_038539890.1 cyclic GMP-AMP synthase isoform X4

CGAS Protein Structure

PRK07003

PRK07003: cl35530 (7 - 149)

Mab-21

Mab-21: pfam03281 (202 - 500)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 513 a.a.
Protein Preferred Names Protein Names

cyclic GMP-AMP synthase

Mab-21 domain containing 1

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-13902 Berzosertib 99.67% Phase 2
HY-13735H Quinacrine acetate / Phase 2
Pre-clinical Phase
Bioactive Molecules (91)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114180 RU.521 Inhibitor 99.95% Unkown
HY-131454 SR-717 Agonist 99.89% Unkown
HY-133916 G140 Inhibitor 99.17% Unkown
HY-128583 G150 Inhibitor 99.20% Unkown
HY-160225 ISD sodium 98.02% Unkown
HY-150751 ODN TTAGGG 99.87% Unkown
HY-114182 PF-06928215 Inhibitor 99.68% Unkown
HY-P1680 Astin C Inhibitor 99.47% Unkown
HY-150751C ODN TTAGGG sodium Antagonist 93.80% Unkown
HY-W021040 Fludioxonil 99.94% Unkown
HY-172208 PROTAC cGAS degrader-1 Degrader 99.07% Unkown
HY-139056 SU0268 Inhibitor 99.96% Unkown
HY-160546 cGAS-IN-2 Inhibitor 99.67% Unkown
HY-149526 cGAS-IN-1 Inhibitor 98.21% Unkown
HY-P5997 XQ2B Inhibitor 99.45% Unkown
HY-114181 IRAK4-IN-4 Inhibitor 99.55% Unkown
HY-123230 Trifloxystrobin Inhibitor 99.49% Unkown
HY-164288 TDI-6570 Inhibitor 99.64% Unkown
HY-131454A SR-717 free acid Agonist 99.36% Unkown
HY-170362 cGAS-IN-4 Inhibitor 99.28% Unkown
HY-116214 Cyprodinil 98.84% Unkown
HY-124700 LYPLAL1-IN-1 99.9% Unkown
HY-158045 PROTAC PARP1 degrader-1 Degrader 99.86% Unkown
HY-174801 XL-3156 Inhibitor 99.91% Unkown
HY-N2616 Vomicine Inhibitor 99.85% Unkown
HY-174802 XL-3158 Inhibitor 99.55% Unkown
HY-141831 STF-1084 Inhibitor 99.92% Unkown
HY-B1331 Cyromazine 99.79% Unkown
HY-170362A (R)-cGAS-IN-4 Control 99.94% Unkown
HY-RS02576 CGAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-177338 STING agonist-45 Agonist 99.10% Unkown
HY-132221 CU-32 Inhibitor 98.8% Unkown
HY-123230R Trifloxystrobin (Standard) Inhibitor 99.15% Unkown
HY-171692 G3-YSD 98.37% Unkown
HY-116214R Cyprodinil (Standard) 99.04% Unkown
HY-RS02577 Cgas Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W411604 tert-Butyl hex-5-ynoate / Unkown
HY-118578 Furalaxyl Inhibitor 99.3% Unkown
HY-12464 Butafenacil / Unkown
HY-116214S Cyprodinil-d5 / Unkown
HY-116214S1 Cyprodinil-13C6 / Unkown
HY-123230S Trifloxystrobin-d6 Inhibitor / Unkown
HY-123230S1 Trifloxystrobin-d3 / Unkown
HY-13902A Berzosertib hydrochloride / Unkown
HY-144328 STING agonist-10 Activator / Unkown
HY-144329 STING agonist-11 Activator / Unkown
HY-147129 cGAS-IN-9 Inhibitor / Unkown
HY-150751A Biotin-labeled ODN TTAGGG sodium / Unkown
HY-150751B FITC-labeled ODN TTAGGG sodium Antagonist / Unkown
HY-158126 G-quadruplex ligand 2 Inhibitor / Unkown
HY-159925 QKY-613 Activator 98.24% Unkown
HY-162459 cGAS-IN-3 Inhibitor / Unkown
HY-162944 NA-Ir / Unkown
HY-162966 MS7829 / Unkown
HY-162967 MS8588 Degrader / Unkown
HY-163461 4F-DDC Inhibitor / Unkown
HY-169225 PDIC-NN Inducer / Unkown
HY-169225A PDIC-NN dimethanesulfonate / Unkown
HY-172218 Lenalidomide-hex-5-ynoic acid / Unkown
HY-175472 (GalNAc)3-CPT / Unkown
HY-176256 endo-S-cGAFMP Agonist / Unkown
HY-178032 PARP1-IN-44 / Unkown
HY-178431 MT-44 / Unkown
HY-179147 cGAS-IN-6 Inhibitor / Unkown
HY-179624 cGAS-IN-7 Inhibitor / Unkown
HY-180211 cGAS-IN-8 Inhibitor / Unkown
HY-180555 SN38-(PEG)2-Pom-α Activator / Unkown
HY-181850 Telomeric G4s ligand 2 / Unkown
HY-182360 Cytisine-platinum(IV) prodrug-1 / Unkown
HY-182758 Topoisomerase I-IN-21 / Unkown
HY-182926 Topoisomerase I/II-IN-9 Inhibitor / Unkown
HY-183748 XL-20 / Unkown
HY-N12507 Eupenicisirenin C Inhibitor / Unkown
HY-N15159 Cladophorol A Inhibitor / Unkown
HY-P3041 Chromostatin (bovine) Inhibitor / Unkown
HY-P3864 Pancreastatin (37-52), human Inhibitor / Unkown
HY-RS02575 CGA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02578 Cgas Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W020788 Benoxacor 99.39% Unkown
HY-114730 CGA-JK3 Inhibitor / Unkown
HY-165620 Etacelasil / Unkown
HY-RS17789 Cga Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24257 Cga Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W010319S 2-Amino-4-methoxy-6-methyl-1,3,5-triazine-d3 / Unkown
HY-W021040S Fludioxonil-13C3 / Unkown
HY-W289054S (S)-Metolachlor metabolite CGA 50720-d3 / Unkown
HY-W681867 Fluxofenim 98.03% Unkown
HY-W714168S (rac)-Metolachlor metabolite CGA 351916-d3 / Unkown
HY-W714705S (S)-Metolachlor metabolite CGA 368208-d3 sodium salt / Unkown
HY-W722289S (rac)-Metolachlor metabolite CGA 50267-d3 / Unkown
HY-W751253 Dofenapyn / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990181 Anti-Mouse myeloperoxidase/MPO Antibody (6G4) Inhibitor 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CGAS NCBI NCBI:115004
Mus musculus CGAS NCBI NCBI:214763