MORF4L2 - mortality factor 4 like 2 Gene

Homo sapiens

Also known as MRGX; MORFL2

Gene ID: 9643 | Gene type: protein coding

About MORF4L2

Cytogenetic location: Xq22.2 Genomic coordinates (GRCh38): X:103,675,498-103,688,047 (from NCBI)

This gene has 13 transcripts (splice variants), 123 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 110.4), endometrium (RPKM 100.8) and 25 other tissues.

Summary

Predicted to be involved in heterochromatin assembly and histone modification. Predicted to act upstream of or within positive regulation of striated muscle cell differentiation and positive regulation of transcription by RNA polymerase II. Located in nucleolus; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MORF4L2 Products(16)

mRNA	Protein	Name
NM_001142418.2	NP_001135890.1	mortality factor 4-like protein 2
NM_001142419.2	NP_001135891.1	mortality factor 4-like protein 2
NM_001142420.2	NP_001135892.1	mortality factor 4-like protein 2
NM_001142421.2	NP_001135893.1	mortality factor 4-like protein 2
NM_001142422.2	NP_001135894.1	mortality factor 4-like protein 2
NM_001142423.2	NP_001135895.1	mortality factor 4-like protein 2
NM_001142424.2	NP_001135896.1	mortality factor 4-like protein 2
NM_001142425.2	NP_001135897.1	mortality factor 4-like protein 2
NM_001142426.2	NP_001135898.1	mortality factor 4-like protein 2
NM_001142427.2	NP_001135899.1	mortality factor 4-like protein 2
NM_001142428.2	NP_001135900.1	mortality factor 4-like protein 2
NM_001142429.2	NP_001135901.1	mortality factor 4-like protein 2
NM_001142430.2	NP_001135902.1	mortality factor 4-like protein 2
NM_001142431.2	NP_001135903.1	mortality factor 4-like protein 2
NM_001142432.2	NP_001135904.1	mortality factor 4-like protein 2
NM_012286.3	NP_036418.1	mortality factor 4-like protein 2

MORF4L2 Protein Structure

MRG

0
100
200
288 a.a.

Protein Preferred Names

Protein Names

mortality factor 4-like protein 2

MORF-related gene X protein

Recombinant MORF4L2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70839	MORF4L2 Protein, Human (His)	Q15014 (M1-L288)	≥95%

Related Diseases

Diseases

Alias

Paraneoplastic Cerebellar Degeneration

Pcd	Paraneoplastic Cerebellar Ataxia
Rapidely Progressive Cerebellar Syndrome	Subacute Cerebellar Degeneration

Pelizaeus-Merzbacher Disease

PMD	HLD1
Pelizaeus-Merzbacher Brain Sclerosis	Leukodystrophy, Hypomyelinating, 1
Diffuse Familial Brain Sclerosis	Pelizaeus Merzbacher Brain Sclerosis
Sudanophilic Leukodystrophy, Paelizeus-Merzbacher Type	Cockayne-Pelizaeus-Merzbacher Disease
Hypomyelinating Leukodystrophy 1	Leukodystrophy, Sudanophilic
Pelizaeus Merzbacher Disease	Hypomyelinating Leukodystrophy, 1
Sudanophilic Leukodystrophy	Pelizaeus-Merzbacher Disease, Connatal Form
Connatal Pmd	Pelizaeus-Merzbacher Disease Type Ii
Severe Pmd	Null Syndrome
Plp1 Null Syndrome	Pelizaeus-Merzbacher Disease, Null Syndrome
Brain Sclerosis Diffuse Familial	Sudanophilic Leukodystrophy Paelizeus-Merzbacher Type
Leukodystrophy Hypomyelinating 1	Diffuse Cerebral Sclerosis Of Schilder

Hypomyelinating Leukodystrophy

Hld	Leukodystrophy, Hypomyelinating

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08594	MORF4L2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MORF4L2	RGD	RGD:1359471
Mus musculus	MORF4L2	MGD	MGI:1927167
Macaca mulatta	MORF4L2	VGNC	VGNC:103833
Bos taurus	MORF4L2	VGNC	VGNC:31557
Felis catus	MORF4L2	VGNC	VGNC:103736
Canis familiaris	MORF4L2	VGNC	VGNC:43320
Others	MORF4L2	NCBI

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