1. Immunology/Inflammation
  2. COX
  3. Hamaudol

Hamaudol 

Cat. No.: HY-N6891
Handling Instructions

Hamaudol is a chromone isolated from Saposhnikovia divaricata. Hamaudol shows significant inhibitory activity on cyclooxygenase (COX)-1 and COX-2 activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects.

For research use only. We do not sell to patients.

Hamaudol Chemical Structure

Hamaudol Chemical Structure

CAS No. : 735-46-6

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Description

Hamaudol is a chromone isolated from Saposhnikovia divaricata. Hamaudol shows significant inhibitory activity on cyclooxygenase (COX)-1 and COX-2 activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects[1][2].

IC50 & Target[2]

COX-1

0.3 mM (IC50)

COX-2

0.57 mM (IC50)

In Vivo

Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency[1].

Molecular Weight

276.28

Formula

C₁₅H₁₆O₅

CAS No.

735-46-6

SMILES

OC1=C2C(OC(C)(C)[[email protected]@H](O)C2)=CC3=C1C(C=C(C)O3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

HamaudolCOXCyclooxygenaseInhibitorinhibitorinhibit

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