hCAIX-IN-10
hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.
For research use only. We do not sell to patients.
- CAS No.: 2497504-72-8
- Formula: C28H21N3O3S
- Molecular Weight:479.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
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CA IX |
Chemical Information
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CAS No. 2497504-72-8
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Molecular Weight 479.55
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Formula C28H21N3O3S
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SMILES
O=C1N(C2=CC=CC(C)=C2)C(C3=CN(C4=CC=CC=C4)N=C3C5=CC6=CC=CC=C6OC5=O)SC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hCAIX-IN-10 Related Classifications
HY-147827 Related Classifications
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