2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC6-IN-30

HDAC6-IN-30 (compound 8g) is a selective HDAC6 inhibitor with the IC50 21 nM, and increase cell protein acetylation levels.

For research use only. We do not sell to patients.

HDAC6-IN-30

HDAC6-IN-30 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

HDAC6-IN-30 Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

HDAC6-IN-30 (compound 8g) is a selective HDAC6 inhibitor with the IC50 21 nM, and increase cell protein acetylation levels[1].

Cellular Effect
Cell Line Type Value Description References
HeLa GI50
80 μM
Compound: 8g
Antiproliferative activity against human HeLa cells assessed as growth inhibition incubated for 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition incubated for 72 hrs by MTS assay
[PMID: 38142511]
MDA-MB-231 GI50
87 μM
Compound: 8g
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by MTS assay
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by MTS assay
[PMID: 38142511]
NCI-H1975 GI50
13 μM
Compound: 8g
Antiproliferative activity against human NCI-H1975 cells assessed as growth inhibition incubated for 96 hrs by MTS assay
Antiproliferative activity against human NCI-H1975 cells assessed as growth inhibition incubated for 96 hrs by MTS assay
[PMID: 38142511]
Molecular Weight

360.41

Formula

C22H20N2O3
SMILES

O=C(NO)C(C=C1)=CC=C1CN(C(C2=CC=CC=C2)=O)CC3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

HDAC6-IN-30 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC6-IN-30HDACHistone deacetylasesEpigeneticsHistone deacetylase 6Lung cancerSmall moleculeInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
HDAC6-IN-30
Cat. No.:
HY-157436
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.