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HJC0197 

Cat. No.: HY-117958
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HJC0197 is a potent exchange proteins directly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2). HJC0197 selectively blocks cAMP-induced Epac activation.

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HJC0197 Chemical Structure

HJC0197 Chemical Structure

CAS No. : 1383539-73-8

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Description

HJC0197 is a potent exchange proteins directly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2). HJC0197 selectively blocks cAMP-induced Epac activation[1].

In Vitro

HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP[1]

Molecular Weight

339.45

Formula

C₁₉H₂₁N₃OS

CAS No.

1383539-73-8

SMILES

N#CC1=C(C2CCCC2)N=C(SCC3=CC(C)=CC=C3C)NC1=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

HJC0197HJC 0197HJC-0197OtherscellularprocessescAMP-signalingactivationphosphorylationGEFInhibitorinhibitorinhibit

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HJC0197
Cat. No.:
HY-117958
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