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Dapirolizumab

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Based on 1 publication(s) in Google Scholar

Dapirolizumab is a PEG-free antigen-binding (Fab') fragment that binds CD40L (CD154) and lacks a functional Fc domain. Dapirolizumab inhibits CD40L-dependent immune responses without causing thrombotic complications and can be used in research related to systemic lupus erythematosus.

For research use only. We do not sell to patients.

  • Purity : 99.66%
  • CAS No.: 2235418-88-7
  • Molecular Weight:145.5 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Dapirolizumab
  • Experimental Validation Results for Dapirolizumab
  • Dapirolizumab Chemical Structure
    Dapirolizumab Chemical Structure
CAS No.: 2235418-88-7
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Dapirolizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Flow cytometric analysis of 1X106 500 ng/mL anti-CD3 stimulated Jurkat cells (24h) with Dapirolizumab (HY-P99842A, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Dapirolizumab Chemical Structure
    1/16
  • Dapirolizumab
  • Flow cytometric analysis of 1X106 500 ng/mL anti-CD3 stimulated Jurkat cells (24h) with Dapirolizumab (HY-P99842A, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa