Urethane-d5
Based on 1 Customer Validation
Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro.
For research use only. We do not sell to patients.
- Purity: 98.5%
- CAS No.: 73962-07-9
- Formula: C3H2D5NO2
- Molecular Weight:94.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 73962-07-9
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Unlabeled Cas 51-79-6
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Appearance Solid
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Molecular Weight 94.12
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Formula C3H2D5NO2
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Color White to light brown
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SMILES
NC(OC([2H])([2H])C([2H])([2H])[2H])=O
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Synonyms
Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (1062.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. K J Field, et al. Hazards of urethane (ethyl carbamate): a review of the literature. Lab Anim. 1988 Jul;22(3):255-62.;R E Sotomayor, et al. Mutagenicity, metabolism, and DNA interactions of urethane. Toxicol Ind Health. 1990 Jan;6(1):71-108. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.6247 mL | 53.1237 mL | 106.2473 mL | 265.6184 mL |
| 5 mM | 2.1249 mL | 10.6247 mL | 21.2495 mL | 53.1237 mL | |
| 10 mM | 1.0625 mL | 5.3124 mL | 10.6247 mL | 26.5618 mL | |
| 15 mM | 0.7083 mL | 3.5416 mL | 7.0832 mL | 17.7079 mL | |
| 20 mM | 0.5312 mL | 2.6562 mL | 5.3124 mL | 13.2809 mL | |
| 25 mM | 0.4250 mL | 2.1249 mL | 4.2499 mL | 10.6247 mL | |
| 30 mM | 0.3542 mL | 1.7708 mL | 3.5416 mL | 8.8539 mL | |
| 40 mM | 0.2656 mL | 1.3281 mL | 2.6562 mL | 6.6405 mL | |
| 50 mM | 0.2125 mL | 1.0625 mL | 2.1249 mL | 5.3124 mL | |
| 60 mM | 0.1771 mL | 0.8854 mL | 1.7708 mL | 4.4270 mL | |
| 80 mM | 0.1328 mL | 0.6640 mL | 1.3281 mL | 3.3202 mL | |
| 100 mM | 0.1062 mL | 0.5312 mL | 1.0625 mL | 2.6562 mL |
Urethane-d5 Related Classifications
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