iHAC
iHAC is an inhibitor HSP90-anchoring chimera, that covalently binds BRD4 ligand (+)-JQ-1 to HSP90, and inhibits the proliferation of cancer cells. iHAC activates the anti-tumor immune response, inhibits the recurrence and metastasis of 4T1 breast cancer in mouse models.
For research use only. We do not sell to patients.
- Formula: C50H46ClIN16O7S3
- Molecular Weight:1241.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 1241.56
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Formula C50H46ClIN16O7S3
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SMILES
ClC1=CC=C(C2=N[C@@H](CC(NCC3=CN(CCCC(N(CC#N)S(=O)(C4=CC=C(C(NCCCN5C(SC6=CC(OCO7)=C7C=C6I)=NC8=C(N)N=CN=C85)=O)C=C4)=O)=O)N=N3)=O)C9=NN=C(C)N9C%10=C2C(C)=C(C)S%10)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)