STF-1623
Based on 1 Customer Validation
STF-1623 is a highly potent ENPP1 inhibitor with an IC50 of 0.6 nM. STF-1623 inhibits ENPP1, activates tumor-specific STING signaling. STF-1623 blocks breast, pancreatic, colon, and brain cancer progression.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 2298391-60-1
- Formula: C16H22N3O4P
- Molecular Weight:351.34
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 0.6 nM (ENPP1)[1]
Chemical Information
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CAS No. 2298391-60-1
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Appearance Oil
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Molecular Weight 351.34
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Formula C16H22N3O4P
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Color Light yellow to yellow
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SMILES
O=P(O)(O)CCC1CCN(C=2N=CN=C3C(OC)=CC=CC32)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (142.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8462 mL | 14.2312 mL | 28.4625 mL | 71.1561 mL |
| 5 mM | 0.5692 mL | 2.8462 mL | 5.6925 mL | 14.2312 mL | |
| 10 mM | 0.2846 mL | 1.4231 mL | 2.8462 mL | 7.1156 mL | |
| 15 mM | 0.1897 mL | 0.9487 mL | 1.8975 mL | 4.7437 mL | |
| 20 mM | 0.1423 mL | 0.7116 mL | 1.4231 mL | 3.5578 mL | |
| 25 mM | 0.1138 mL | 0.5692 mL | 1.1385 mL | 2.8462 mL | |
| 30 mM | 0.0949 mL | 0.4744 mL | 0.9487 mL | 2.3719 mL | |
| 40 mM | 0.0712 mL | 0.3558 mL | 0.7116 mL | 1.7789 mL | |
| 50 mM | 0.0569 mL | 0.2846 mL | 0.5692 mL | 1.4231 mL | |
| 60 mM | 0.0474 mL | 0.2372 mL | 0.4744 mL | 1.1859 mL | |
| 80 mM | 0.0356 mL | 0.1779 mL | 0.3558 mL | 0.8895 mL | |
| 100 mM | 0.0285 mL | 0.1423 mL | 0.2846 mL | 0.7116 mL |