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Cat. No.: HY-187850

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Isovanillobiocin

Isovanillobiocin is an aminocoumarin Antibiotic. Isovanillobiocin can be isolated from a cloQ-deficient mutant of Streptomyces roseochromogenes. Isovanillobiocin inhibits the growth of Bacillus subtilis. Isovanillobiocin can be used in studies of bacterial growth inhibition.

For research use only. We do not sell to patients.

CAS No.: 744218-19-7
Formula: C₃₁H₃₁ClN₂O₁₂
Molecular Weight:659.04

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Isovanillobiocin Chemical Structure

CAS No.: 744218-19-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

Microbial Metabolite

All Antibiotic Isoforms :

All Endogenous Metabolite Isoforms :

In Vitro

Isovanillobiocin exhibits antibacterial activity against Bacillus subtilis ATCC 14893, with activity similar to that of Vanillobiocin (HY-N21934)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 744218-19-7
Molecular Weight 659.04
Formula C₃₁H₃₁ClN₂O₁₂
SMILES

OC(C1=CC=C(O[C@H]2[C@@H]([C@@H]([C@H](C(C)(O2)C)OC)O)OC(C3=CC=C(C)N3)=O)C(Cl)=C1O4)=C(NC(C5=CC(OC)=C(C=C5)O)=O)C4=O
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
- Microorganisms
treptomyces roseochromogenes subsp. oscitans DS 12.976
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Aerobic Bacterial Batch Culture on Broth/Agar
Aerobic bacterial batch culture grows a closed inoculated population in broth or on agar without continuous medium replacement; growth readouts include turbidity/OD for total suspended biomass and colony-forming units for viable cells able to form colonies on agar. OD-based growth curves reflect light scattering by cells, but OD is instrument-, pathlength-, species-, cell-size-, and density-dependent, so OD should be calibrated or interpreted alongside viable counts when quantitative cell density is required.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Freitag A, et al. New aminocoumarin antibiotics from a cloQ-defective mutant of the clorobiocin producer Streptomyces roseochromogenes DS12.976. The Journal of antibiotics. 2004 Mar;57(3):205-9.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

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100 mg

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