GEN-1053
Based on 1 Customer Validation
GEN-1053 (BNT-313) is a fully human IgG1 antibody that targets CD27. GEN-1053 binds to CD27 and forms a hexamer upon binding. The isotype control for GEN-1053 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992).
For research use only. We do not sell to patients.
- Purity : 99.72%
- CAS No.: 2733575-82-9
- Molecular Weight:143.727 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD27
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-lambda
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD27/TNFRSF7 Protein, Human (HEK293, His-Fc, HY-P72742) can bind GEN-1053. The EC50 for this effect is 18.35 ng/mL.
Chemical Information
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CAS No. 2733575-82-9
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Appearance Liquid
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Molecular Weight 143.727 kDa
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Color Colorless to light yellow
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SMILES
[GEN-1053]
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Synonyms
BNT-313; Tixestobart
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (254 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)