TMB-8
Based on 1 Customer Validation
TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 53464-72-5
- Formula: C22H38ClNO5
- Molecular Weight:431.99
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Calcium Channel Isoforms
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Biological Activity
Chemical Information
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CAS No. 53464-72-5
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Appearance Solid
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Molecular Weight 431.99
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Formula C22H38ClNO5
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Color White to off-white
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SMILES
COC1=C(C(OC)=CC(C(OCCCCCCCCN(CC)CC)=O)=C1)OC.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (115.74 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3149 mL | 11.5743 mL | 23.1487 mL | 57.8717 mL |
| 5 mM | 0.4630 mL | 2.3149 mL | 4.6297 mL | 11.5743 mL | |
| 10 mM | 0.2315 mL | 1.1574 mL | 2.3149 mL | 5.7872 mL | |
| 15 mM | 0.1543 mL | 0.7716 mL | 1.5432 mL | 3.8581 mL | |
| 20 mM | 0.1157 mL | 0.5787 mL | 1.1574 mL | 2.8936 mL | |
| 25 mM | 0.0926 mL | 0.4630 mL | 0.9259 mL | 2.3149 mL | |
| 30 mM | 0.0772 mL | 0.3858 mL | 0.7716 mL | 1.9291 mL | |
| 40 mM | 0.0579 mL | 0.2894 mL | 0.5787 mL | 1.4468 mL | |
| 50 mM | 0.0463 mL | 0.2315 mL | 0.4630 mL | 1.1574 mL | |
| 60 mM | 0.0386 mL | 0.1929 mL | 0.3858 mL | 0.9645 mL | |
| 80 mM | 0.0289 mL | 0.1447 mL | 0.2894 mL | 0.7234 mL | |
| 100 mM | 0.0231 mL | 0.1157 mL | 0.2315 mL | 0.5787 mL |