Copy Link Print Information

Oxytocin

(別名: α-Hypophamine; Oxytocic hormone)
28 Cited Publications
カスタマーレビュー

Based on 28 publication(s) in Google Scholar

Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.87%
  • CAS 番号: 50-56-6
  • 分子式: C43H66N12O12S2
  • 分子量:1007.19
  • 保管条件:

    Sealed storage, away from moisture.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Oxytocin Chemical Structure
    Oxytocin 構造式
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
  • Experimental Validation Results for Oxytocin
CAS 番号: 50-56-6
容量
価格（税別）
在庫状況
数量
Amount: USD 0.00
Please select quantity
or
or

* アイテムを追加する前、数量をご選択ください

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Oxytocin:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
  • 生物活性
  • 化学情報
  • 溶剤 & 溶解度
  • 純度とドキュメンテーション
  • 参考文献
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

MedChemExpress（MCE）の使用を引用している文献 Oxytocin

More
Customer Validation & Images
IFRT-PCRWBIn Vivo Efficacy StudyHistological Imaging/Staining
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study
  • Histological Imaging/Staining
  • RT-PCR
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study
  • IF
  • WB
  • In Vivo Efficacy Study

Endogenous Metabolite アイソフォーム固有の製品をすべて表示

More
Keywords
100 mg

お問い合わせ 在庫あり

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress ログイン
Register
Sign in to MedChemExpress
新規会員登録

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Oxytocin Chemical Structure
    Oxytocin Chemical Structure
    1/16
  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Transl Psychiatry. 2024 May 25;14(1):208. [Abstract]

    Customer Validation
     Trajectories of PEL-treated group (n = 6), AVP-supplemented group (n = 6), Oxytocin acetate (administered intraperitoneally 1 mg/kg/d for i.p., 50 ng for hippocampal stereotactic injection)-supplemented group (n = 6), and ATO group (n = 6) in the MWM place navigation experiment.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Transl Psychiatry. 2024 May 25;14(1):208. [Abstract]

    Customer Validation
     Trajectories of PEL-treated group (n = 6), AVP-supplemented group (n = 6), Oxytocin acetate (administered intraperitoneally 1 mg/kg/d for i.p., 50 ng for hippocampal stereotactic injection)-supplemented group (n = 6), and ATO group (n = 6) in the MWM spatial exploration experiment. The shaded part is the area around the platform, and the activity time of mice in the shaded part is calculated.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Transl Psychiatry. 2024 May 25;14(1):208. [Abstract]

    Customer Validation
     Validation of activation of endogenous Oxytocin acetate neurons in mice with PVN Oxytocin acetate neurons activated after PEL surgery.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Psychoneuroendocrinology. 2024 Oct:168:107138. [Abstract]

    Customer Validation
     Expression of OT (Oxytocin) signaling related genes in the hippocampus. RT-PCR analysis were performed on brain tissues from the hippocampus. Con: control; Veh: Vehicle (Saline); RIS: Risperidone; LOT: Low dose (6 μg/kg) of OT; MOT: Medium dose (20 μg/kg) of OT; HOT: High dose (60 μg/kg) of OTAfter 1 week of acclimation, animals in the control group were administered saline (10 ml/kg) and those in the model group were administered MK801 (0.6 mg/kg) through intraperitoneal (i. p.) injections once a day for 21 days. One week after MK801 administration, 6 μg/kg OT (LOT group, n = 10), 20 μg/kg OT (MOT group, n = 10), or 60 μg/kg OT (HOT group, n = 10) was given through the i.n. route twice daily, at 8:30–9:30 AM and 4:00–5:00 PM, for 14 days. Saline (0.2 μL/g) was administered intranasally in the control and vehicle groups. Then, the mice received an i.p. injection of MK801 30 min after OT administration. The mice in the RIS group received an i.p. injection of 0.3 mg/kg RIS once daily for 14 days

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Psychoneuroendocrinology. 2024 Oct:168:107138. [Abstract]

    Customer Validation
     Effects of chronic intranasal OT (Oxytocin) on levels of spontaneous activity and anxiety-like behaviors in MK801-induced mice Fig. A, the total distance traveled by the mice in the open field test. Fig. 2B, the ratio of distance traveled in the central versus peripheral zone by the mice in the open field test. Con: control; Veh: Vehicle (Saline); RIS: Risperidone; LOT: Low dose (6 μg/kg) of OT; MOT: Medium dose (20 μg/kg) of OT; HOT: High dose (60 μg/kg) of OTAfter 1 week of acclimation, animals in the control group were administered saline (10 ml/kg) and those in the model group were administered MK801 (0.6 mg/kg) through intraperitoneal (i.p.) injections once a day for 21 days. One week after MK801 administration, 6 μg/kg OT (LOT group, n = 10), 20 μg/kg OT (MOT group, n =10), or 60 μg/kg OT (HOT group, n = 10) was giventhrough the i.n. route twice daily, at 8:30–9:30 AM and 4:00–5:00 PM, for 14 days. Saline (0.2 μL/g) was administered intranasally in the control and vehicle groups. Then, the mice received ani.p. injection of MK801 30 min after OT administration. The mice in the RIS group received an i.p. injection of 0.3 mg/kg RIS once daily for 14 days.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 Jan 2;8(1):3. [Abstract]

    Customer Validation
     Representative heatmaps showing the duration and location of the shControl and shScgn mice during the 10 min social novelty recognition test. Warmer colors (red) indicate a greater amount of time spent exploring by the mice. shControl: PVN Control-shRNA injection mouse. shScgn: PVN Scgn-shRNA injection mouse. DMSO: 0.1% DMSO administration. Oxytocin acetate: 1 mg/kg Oxytocin administration. S1: a familiar mouse. S2: a novel mouse.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 Jan 2;8(1):3. [Abstract]

    Customer Validation
     Statistics of marbles burying numbers in shControl and shScgn mice treated with DMSO or Oxytocin acetate.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: J Headache Pain. 2021 Jul 27;22(1):84. [Abstract]

    Customer Validation
     Effect of OT on CGRP and c-fos expression levels. A and C show c-fos, B and D show CGRP. Immunofluorescence staining showed that the number of c-fos-positive cells per FOV and the average fluorescence intensity of CGRP were significantly increased in the NTG + vehicle group compared with the sham group. OT administration significantly reduced the expression of CGRP and c-fos, while these effects were prevented after adding L368,899. Repeated OT (Oxytocin, 20 µg/kg) treatments were quickly administered at 2 µL per nostril or the same volume of saline every two minutes using the tip of the pipette 30 min before NTG and then once daily at the same time point for 11 days.C57BL/6 mice weighing 20 ~ 30 g and 6 ~ 8 weeks of age.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: J Headache Pain. 2021 Jul 27;22(1):84. [Abstract]

    Customer Validation
     WB data quantification in the mouse trigeminal nucleus caudalis. Repeated OT (Oxytocin, 20 µg/kg) treatments were quickly administered at 2 µL per nostril or the same volume of saline every two minutes using the tip of the pipette 30 min before NTG and then once daily at the same time point for 11 days.C57BL/6 mice weighing 20 ~ 30 g and 6 ~ 8 weeks of age.

  • 1/16

    Oxytocin purchased from MedChemExpress. Usage Cited in: J Headache Pain. 2021 Jul 27;22(1):84. [Abstract]

    Customer Validation
     OT ameliorated pain sensitization and reduced neuronal activation via OTR. Note that L-368,899 was intraperitoneally injected daily 1 h before OT treatment. The mechanical and thermal pain thresholds of the hind paw and periorbital area were assessed before each NTG injection and on day 11. B, C, D The basal mechanical pain thresholds of the hind paw (B), periorbital area (C), and the thermal pain response of the hind paw (D) were significantly increased in the NTG + OT group compared with the NTG + vehicle group.The pain threshold in the NTG + OT + L368,899 group was markedly decreased compared with the NTG + OT group.Repeated OT (Oxytocin, 20 µg/kg) treatments were quickly administered at 2 µL per nostril or the same volume of saline every two minutes using the tip of the pipette 30 min before NTG and then once daily at the same time point for 11 days.C57BL/6 mice weighing 20 ~ 30 g and 6 ~ 8 weeks of age.

  • Oxytocin