Anticancer agent 347
Anticancer agent 347 is a heterobifunctional anticancer inhibitor with inhibitory activity against ERα-overexpressing cells and breast cancer cells. Anticancer agent 347 can be used for the research of breast cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3099595-91-9
- 分子式: C46H53F3N10O3S
- 分子量:883.04
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
ERα |
Anticancer agent 347 (I-33) exhibits potent antiproliferative activity against MCF7 breast cancer cells (GI50 < 0.05 μM)[1].
Anticancer agent 347 exerts potent and selective antiproliferative effects on Doxorubicin (HY-15142A)-induced estrogen receptor α-overexpressing T-Rex 293 cells (GI50 < 0.05 μM), while shows extremely weak inhibitory activity against T-Rex 293 cells without high estrogen receptor α expression (GI50 > 2.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 3099595-91-9
-
分子量 883.04
-
分子式 C46H53F3N10O3S
-
SMILES
FC(F)(F)CN1[C@H](C2=CC=C(C=N2)NC3CN(C3)CCCOCCOCCOC4=CC=C(C5=N[C@@H](C)C6=NN=C(C)N6C7=C5C(C)=C(C)S7)C=C4)C8=C(C[C@H]1C)C9=CNN=C9C=C8
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 347 関連分類
HY-184948 関連分類
Powered by Bioz