Antimalarial agent 36
Antimalarial agent 36 (compound 1) is an antimalarial agent, with the EC50s of 58 nM and 42 nM, for Dd2 and 3D7, respectively. Antimalarial agent 36 targets EphA2.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2982633-03-2
- 分子式: C31H29ClF3N5O2S
- 分子量:628.11
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
2590 nM
Compound: 1
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 38214254] |
| MCF7 | EC50 |
3510 nM
Compound: 1
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
|
[PMID: 38214254] |
化学情報
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CAS 番号 2982633-03-2
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分子量 628.11
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分子式 C31H29ClF3N5O2S
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SMILES
O=C(C1=CC(C2=CC=CS2)=CN=C1)NC3=CC(Cl)=CC(C(NC4=CC=C(C(C(F)(F)F)=C4)CN5CCN(CC5)CC)=O)=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)