Antimalarial agent 8
Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2715222-97-0
- 分子式: C22H21Cl3N4O
- 分子量:463.79
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Plasmodium |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
32 μM
Compound: 7e.HCl
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Cytotoxicity against human HEK293 cells by resazurin based cell viability assay
Cytotoxicity against human HEK293 cells by resazurin based cell viability assay
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[PMID: 35300096] |
| Hepatocyte | CC50 |
8500 nM
Compound: 7e.HCl
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Cytotoxicity against human hepatocytes measured after 96 hrs by DAPI staining based fluroscence assay
Cytotoxicity against human hepatocytes measured after 96 hrs by DAPI staining based fluroscence assay
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[PMID: 35300096] |
化学情報
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CAS 番号 2715222-97-0
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分子量 463.79
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分子式 C22H21Cl3N4O
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SMILES
O=C(C1=CC2=C(NC3=C2C=CC=C3C)C(C4=CC(Cl)=C(Cl)C=C4)=N1)NCCNC.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antimalarial agent 8 関連分類
HY-145704 関連分類
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