Benzydamine
Benzydamine is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 642-72-8
- 分子式: C19H23N3O
- 分子量:309.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf21 | EC50 |
1.02 μM
Compound: 3
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Activation of bovine sGC Enzyme (soluble Guanylate Cyclase) in Sf21 cells infected with baculo virus in the presence of 30 nM of PAPA/NO
Activation of bovine sGC Enzyme (soluble Guanylate Cyclase) in Sf21 cells infected with baculo virus in the presence of 30 nM of PAPA/NO
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[PMID: 11141091] |
Benzydamine has a MIC of 0.5 mg/mL and a MLC of 1.0 mg/mL against Escherichia coli, ATCC 8739, and a MIC of 1.0 mg/mL and a MLC of 1.0 mg/mL against Proteus vulgaris, ATCC 13315[1].
Benzydamine (1.0 mg/mL, 24 h) inhibits the proliferation of Ps. Aeruginosa[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Ps. aeruginosa
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Concentration:1.0 mg/mL
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Incubation Time:24 h
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Result:Inhibited the proliferation of Ps. aeruginosa.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 642-72-8
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分子量 309.41
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分子式 C19H23N3O
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SMILES
CN(C)CCCOC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. [Content Brief]
[2]. Quane PA, Pharmacology of benzydamine. Inflammopharmacology. 1998;6(2):95-107 [Content Brief]
[3]. R S Turnbull, et al. Benzydamine Hydrochloride (Tantum) in the management of oral inflammatory conditions. J Can Dent Assoc. 1995 Feb;61(2):127-34. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Benzydamine 関連分類
HY-30235 関連分類
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