CDL36
CDL36 is a BAX inhibitor with an EC50 of 23.6 µM. CDL36 inhibits pro-apoptotic peptide-induced mitochondrial outer membrane permeabilization (MOMP). CDL36 exerts cytoprotective effects against Doxorubicin (HY-15142A)-induced cell death.
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- CAS 番号: 951529-42-3
- 分子式: C29H32N6O2
- 分子量:496.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
Bax 23.6 μM (EC50) |
体外実験
CDL36 (12.5-25 µM; 72 h) specifically protects intact CRISPR control cells and BAX knockout (KO) A549 cells against 5 µM Doxorubicin (HY-15142A)-induced cell death over a 72-hour treatment period[1].
CDL36 binds to recombinant BAX protein as determined by microscale thermophoresis, with an EC50 of 23.6 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 951529-42-3
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分子量 496.60
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分子式 C29H32N6O2
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SMILES
CN(C1=C2C=CC=C1)C=C2C3=NN(CCC4=O)C(N4CC(N(CC5)CCN5C6=CC=CC(C)=C6C)=O)=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDL36 関連分類
HY-187706 関連分類
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