Cotinine (Standard)
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 486-56-6
- 分子式: C₁₀H₁₂N₂O
- 分子量:176.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 486-56-6
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分子量 176.22
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分子式 C₁₀H₁₂N₂O
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SMILES
O=C1N(C)[C@H](C2=CC=CN=C2)CC1
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別名
(-)-Cotinine (Standard); (S)-Cotinine (Standard); NIH-10498 (Standard)
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Dolcini MM, et al. An assessment of the validity of adolescent self-reported smoking using three biological indicators. Nicotine Tob Res. 2003 Aug;5(4):473-83. [Content Brief]
[2]. Sastry BV, et al. Distribution and retention of nicotine and its metabolite, cotinine, in the rat as a function of time. Pharmacology. 1995 Feb;50(2):128-36. [Content Brief]
[3]. Borzelleca J F, et al. Studies on the respiratory and cardiovascular effects of (-)-cotinine[J]. Journal of Pharmacology and Experimental Therapeutics, 1962, 137(3): 313-318. [Content Brief]
[4]. Yang Q, et al. Continuous exposure of nicotine and cotinine retards human primary pterygium cell proliferation and migration. [Content Brief]
[5]. Dwoskin L P, et al. (S)-(−)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H] dopamine release from rat striatal slices in a calcium-dependent manner[J]. Journal of pharmacology and experimental therapeutics, 1999, 288(3): 905-911. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)