Daidzein-d4
Based on 1 publication(s) in Google Scholar
Daidzein-d4 is the deuterium labeled Daidzein. Daidzein is a soy isoflavone, which acts as a PPAR activator.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.93%
- CAS 番号: 1219803-57-2
- 分子式: C15H6D4O4
- 分子量:258.26
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-14596S
Genistein-d4Stable Isotope -
HY-16950
4-HydroxytamoxifenEstrogen Receptor Modulator -
HY-16950A
(E/Z)-4-HydroxytamoxifenEstrogen Receptor Modulator -
HY-100583
(-)-(S)-EquolEstrogen Receptor β Ligand -
HY-100583R
(-)-(S)-Equol (Standard)Estrogen Receptor β Ligand -
HY-B0652
EtonogestrelProgesterone/ERR Agonist -
HY-B0652R
Etonogestrel (Standard)Progesterone/ERR Agonist -
HY-103457
Y134Estrogen Receptor Modulator -
HY-16950R
4-Hydroxytamoxifen (Standard)Estrogen Receptor Modulator -
HY-16950AR
(E/Z)-4-Hydroxytamoxifen (Standard)Estrogen Receptor Modulator -
HY-B0110S
Gestodene-d6Stable Isotope -
HY-W745779
Dienogest-d8Stable Isotope
MedChemExpress（MCE）の使用を引用している文献 Daidzein-d4
MoreEndogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
-
CAS 番号 1219803-57-2
-
非標識Cas 486-66-8
-
性状 Solid
-
分子量 258.26
-
分子式 C15H6D4O4
-
Color White to off-white
-
SMILES
O=C1C2=CC=C(O)C=C2OC=C1C3=C([2H])C([2H])=C(C([2H])=C3[2H])O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
溶剤 & 溶解度
体外:
DMSO : ≥ 30 mg/mL (116.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : ≥ 10 mg/mL (38.72 mM)
Ethanol : ≥ 0.1 mg/mL (0.39 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (273 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Sakamoto Y1, et al. The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures. PLoS One. 2016 Feb 22;11(2):e0149676. [Content Brief]
[3]. Kim E, et al. Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke. J Neurosci. 2015 Nov 11;35(45):15113-26. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / DMSO | 1 mM | 3.8721 mL | 19.3603 mL | 38.7207 mL | 96.8017 mL |
| 5 mM | 0.7744 mL | 3.8721 mL | 7.7441 mL | 19.3603 mL | |
| 10 mM | 0.3872 mL | 1.9360 mL | 3.8721 mL | 9.6802 mL | |
| 15 mM | 0.2581 mL | 1.2907 mL | 2.5814 mL | 6.4534 mL | |
| 20 mM | 0.1936 mL | 0.9680 mL | 1.9360 mL | 4.8401 mL | |
| 25 mM | 0.1549 mL | 0.7744 mL | 1.5488 mL | 3.8721 mL | |
| 30 mM | 0.1291 mL | 0.6453 mL | 1.2907 mL | 3.2267 mL | |
| DMSO | 40 mM | 0.0968 mL | 0.4840 mL | 0.9680 mL | 2.4200 mL |
| 50 mM | 0.0774 mL | 0.3872 mL | 0.7744 mL | 1.9360 mL | |
| 60 mM | 0.0645 mL | 0.3227 mL | 0.6453 mL | 1.6134 mL | |
| 80 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2100 mL | |
| 100 mM | 0.0387 mL | 0.1936 mL | 0.3872 mL | 0.9680 mL |
Daidzein-d4 関連分類
HY-N0019S 関連分類
Powered by Bioz