Ebsulfur
Based on 1 Customer Validation
Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.43%
- CAS 番号: 2527-03-9
- 分子式: C13H9NOS
- 分子量:227.28
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HaCaT | IC50 |
>32 μM
Compound: 1b
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Cytotoxicity against human HaCaT cells
Cytotoxicity against human HaCaT cells
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[PMID: 35099959] |
| Vero C1008 | CC50 |
19.43 μM
Compound: 1.1
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Cytotoxicity against monkey Vero C1008 cells after 72 hrs by MTT assay
Cytotoxicity against monkey Vero C1008 cells after 72 hrs by MTT assay
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[PMID: 28159413] |
化学情報
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CAS 番号 2527-03-9
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性状 Solid
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分子量 227.28
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分子式 C13H9NOS
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Color White to off-white
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SMILES
O=C1N(C2=CC=CC=C2)SC3=C1C=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 62.5 mg/mL (274.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3999 mL | 21.9993 mL | 43.9986 mL | 109.9965 mL |
| 5 mM | 0.8800 mL | 4.3999 mL | 8.7997 mL | 21.9993 mL | |
| 10 mM | 0.4400 mL | 2.1999 mL | 4.3999 mL | 10.9996 mL | |
| 15 mM | 0.2933 mL | 1.4666 mL | 2.9332 mL | 7.3331 mL | |
| 20 mM | 0.2200 mL | 1.1000 mL | 2.1999 mL | 5.4998 mL | |
| 25 mM | 0.1760 mL | 0.8800 mL | 1.7599 mL | 4.3999 mL | |
| 30 mM | 0.1467 mL | 0.7333 mL | 1.4666 mL | 3.6665 mL | |
| 40 mM | 0.1100 mL | 0.5500 mL | 1.1000 mL | 2.7499 mL | |
| 50 mM | 0.0880 mL | 0.4400 mL | 0.8800 mL | 2.1999 mL | |
| 60 mM | 0.0733 mL | 0.3667 mL | 0.7333 mL | 1.8333 mL | |
| 80 mM | 0.0550 mL | 0.2750 mL | 0.5500 mL | 1.3750 mL | |
| 100 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1000 mL |
Ebsulfur 関連分類
HY-128170 関連分類
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