eeAChE-IN-3
eeAChE-IN-3 (compound YS3g) is an orally active, potent EeAChE and IL-6 inhibitor with IC50s of 0.54 μM, 0.49 μM, 8.54 μM and 0.57 μM for EeAChE, RatAChE, RatBuChE and IL-6, respectively. eeAChE-IN-3 improves STZ (HY-13753) (Streptozotocin; HY-13753)-induced learning and memory impairment in mice. eeAChE-IN-3 has the potential for Alzheimer's disease (AD) research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C18H25N3O4
- 分子量:347.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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EeAChE 0.54 μM (IC50) |
RatAChE 0.49 μM (IC50) |
RatBuChE 8.54 μM (IC50) |
IL-6 0.57 μM (IC50) |
化学情報
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分子量 347.41
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分子式 C18H25N3O4
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SMILES
O=C1C2=C(OC)C=C(OC)C=C2OC(CCCNN3CCNCC3)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)