Eugenitin
Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 480-12-6
- 分子式: C12H12O4
- 分子量:220.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
LD50: 39.9 μM (Leishmania major)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-8 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human HCT8 cells by colorimetric method
Cytotoxicity against human HCT8 cells by colorimetric method
|
[PMID: 24387625] |
| HL-60 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human HL60 cells by colorimetric method
Cytotoxicity against human HL60 cells by colorimetric method
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[PMID: 24387625] |
| Lymphocyte | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human lymphocytes by colorimetric method
Cytotoxicity against human lymphocytes by colorimetric method
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[PMID: 24387625] |
| MDA-MB-435 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human MDA-MB-435 cells by colorimetric method
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
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[PMID: 24387625] |
| PC-3 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
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[PMID: 24387625] |
| SF-295 | IC50 |
>113 μM
Compound: 3
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Cytotoxicity against human SF295 cells by colorimetric method
Cytotoxicity against human SF295 cells by colorimetric method
|
[PMID: 24387625] |
化学情報
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CAS 番号 480-12-6
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分子量 220.22
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分子式 C12H12O4
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SMILES
O=C1C=C(C)OC2=C1C(O)=C(C)C(OC)=C2
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Structure Classification
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Initial Source
Mycoleptodiscus indicus
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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