AGXT - alanine--glyoxylate aminotransferase Gene

Also Known as AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; Ser-PyrAT

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 189

About AGXT

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:240,868,824-240,880,500 (from NCBI)

This gene has 4 transcripts (splice variants), 258 orthologues, 1 paralogue and is associated with 3 phenotypes. Restricted expression toward liver (RPKM 387.9).

Summary

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]

AGXT Products (1)

mRNA	Protein	Name
NM_000030.3	NP_000021.1	alanine--glyoxylate aminotransferase

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables L-serine-pyruvate transaminase activity	IDA IDA: Inferred from direct assay	10347152	GOA
enables alanine-glyoxylate transaminase activity	IDA IDA: Inferred from direct assay	10960483	GOA
enables alanine-glyoxylate transaminase activity	IMP IMP: Inferred from mutant phenotype	12777626	GOA
enables amino acid binding	IDA IDA: Inferred from direct assay	18492492	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	12899834	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15911627	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	10960483	GOA
enables pyridoxal phosphate binding	IDA IDA: Inferred from direct assay	17696873	GOA
enables pyridoxal phosphate binding	IMP IMP: Inferred from mutant phenotype	15802217	GOA
enables transaminase activity	IDA IDA: Inferred from direct assay	18492492	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in L-alanine catabolic process	IDA IDA: Inferred from direct assay	17696873	GOA
involved in L-cysteine catabolic process	IDA IDA: Inferred from direct assay	18492492	GOA
involved in L-serine metabolic process	IDA IDA: Inferred from direct assay	10347152	GOA
involved in glycine biosynthetic process, by transamination of glyoxylate	IDA IDA: Inferred from direct assay	22198249	GOA
involved in glyoxylate catabolic process	IDA IDA: Inferred from direct assay	22198249	GOA
involved in glyoxylate metabolic process	IDA IDA: Inferred from direct assay	12777626	GOA
involved in glyoxylate metabolic process	IMP IMP: Inferred from mutant phenotype	3709805	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
located in peroxisomal matrix	IDA IDA: Inferred from direct assay	3418107	GOA
located in peroxisome	IDA IDA: Inferred from direct assay	1703535	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AGXT Protein Structure

Aminotran_5

0
100
200
300
392 a.a.

Protein Preferred Names	Protein Names
alanine--glyoxylate aminotransferase	L-alanine: glyoxylate aminotransferase 1

AGXT Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	AGXT	P21549	KRT40	Homo sapiens	Q6A162	Validated Y2H	32296183
Intra	AGXT	P21549	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRT40	Homo sapiens	Q6A162	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP8-1	Homo sapiens	Q8IUC2	Validated Y2H	32296183
Intra	AGXT	P21549	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	BATF3	Homo sapiens	Q9NR55	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	BATF3	Homo sapiens	Q9NR55	Validated Y2H	32296183
Intra	AGXT	P21549	BATF3	Homo sapiens	Q9NR55	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRTAP9-2	Homo sapiens	Q9BYQ4	Validated Y2H	32296183
Intra	AGXT	P21549	KRT37	Homo sapiens	O76014	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRT37	Homo sapiens	O76014	Y2H Array	32296183
Intra	AGXT	P21549	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	AGXT	P21549	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	PRDM6	Homo sapiens	Q9NQX0	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	PRDM6	Homo sapiens	Q9NQX0	Y2H Array	32296183
Intra	AGXT	P21549	PRDM6	Homo sapiens	Q9NQX0	Validated Y2H	32296183
Intra	AGXT	P21549	EFS	Homo sapiens	O43281-2	Y2H Array	32296183
Intra	AGXT	P21549	EFS	Homo sapiens	O43281-2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRTAP12-3	Homo sapiens	P60328	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRTAP12-3	Homo sapiens	P60328	Validated Y2H	32296183
Intra	AGXT	P21549	KRTAP12-3	Homo sapiens	P60328	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	AGXT	P21549	ACTMAP	Homo sapiens	Q5BKX5-3	Validated Y2H	32296183
Intra	AGXT	P21549	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Array	32296183
Intra	AGXT	P21549	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FAM168B	Homo sapiens	A1KXE4-2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FAM168B	Homo sapiens	A1KXE4-2	Y2H Array	32296183
Intra	AGXT	P21549	SPRYD7	Homo sapiens	Q5W111-2	Validated Y2H	32296183
Intra	AGXT	P21549	SPRYD7	Homo sapiens	Q5W111-2	Y2H Array	32296183
Intra	AGXT	P21549	SPRYD7	Homo sapiens	Q5W111-2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	MORN5	Homo sapiens	Q5VZ52	Validated Y2H	32296183
Intra	AGXT	P21549	MORN5	Homo sapiens	Q5VZ52	Y2H Array	32296183
Intra	AGXT	P21549	MORN5	Homo sapiens	Q5VZ52	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	PLEKHG7	Homo sapiens	Q6ZR37	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	PLEKHG7	Homo sapiens	Q6ZR37	Y2H Array	32296183
Intra	AGXT	P21549	PLEKHG7	Homo sapiens	Q6ZR37	Validated Y2H	32296183
Intra	AGXT	P21549	PEX5	Homo sapiens	P50542-1	SLS	22529745
Intra	AGXT	P21549	PEX5	Homo sapiens	P50542-1	X-Ray Diffraction	22529745
Intra	AGXT	P21549	PEX5	Homo sapiens	P50542-1	ITC	22529745
Intra	AGXT	P21549	PEX5	Homo sapiens	P50542-1	GMS	22529745
Intra	AGXT	P21549	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FOSB	Homo sapiens	P53539	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FOSB	Homo sapiens	P53539	Y2H Array	32296183
Intra	AGXT	P21549	FOSB	Homo sapiens	P53539	Validated Y2H	32296183
Intra	AGXT	P21549	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	AGXT	P21549	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	OIP5	Homo sapiens	O43482	Y2H Array	32296183
Intra	AGXT	P21549	FNTB	Homo sapiens	P49356	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FNTB	Homo sapiens	P49356	Validated Y2H	32296183
Intra	AGXT	P21549	FNTB	Homo sapiens	P49356	Y2H Array	32296183
Intra	AGXT	P21549	CFAP68	Homo sapiens	Q9H5F2	Y2H Array	32296183
Intra	AGXT	P21549	CFAP68	Homo sapiens	Q9H5F2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	CFAP68	Homo sapiens	Q9H5F2	Validated Y2H	32296183
Intra	AGXT	P21549	TRAPPC14	Homo sapiens	Q8WVR3	Validated Y2H	32296183
Intra	AGXT	P21549	TRAPPC14	Homo sapiens	Q8WVR3	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	TRAPPC14	Homo sapiens	Q8WVR3	Y2H Array	32296183
Intra	AGXT	P21549	MDFI	Homo sapiens	Q99750	Y2H Array	32296183
Intra	AGXT	P21549	MDFI	Homo sapiens	Q99750	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	MDFI	Homo sapiens	Q99750	Validated Y2H	32296183
Intra	AGXT	P21549	PLA2G10	Homo sapiens	O15496	Y2H Array	32296183
Intra	AGXT	P21549	PLA2G10	Homo sapiens	O15496	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	Validated Y2H	32296183
Intra	AGXT	P21549	KRTAP3-1	Homo sapiens	Q9BYR8	Validated Y2H	32296183
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP3-1	Homo sapiens	Q9BYR8	Y2H Array	32296183
Intra	AGXT	P21549	KRTAP3-1	Homo sapiens	Q9BYR8	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	X-Ray Diffraction	12899834
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	GMS	22529745
Intra	AGXT	P21549	AGXT	Homo sapiens	P21549	SLS	22529745
Intra	AGXT	P21549	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	AGXT	P21549	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	AGXT	P21549	CHIC2	Homo sapiens	Q9UKJ5	Validated Y2H	32296183
Intra	AGXT	P21549	CHIC2	Homo sapiens	Q9UKJ5	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	CHIC2	Homo sapiens	Q9UKJ5	Y2H Array	32296183
Intra	AGXT	P21549	LPXN	Homo sapiens	O60711	Y2H Array	32296183
Intra	AGXT	P21549	LPXN	Homo sapiens	O60711	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	RFX6	Homo sapiens	Q8HWS3	Y2H Array	32296183
Intra	AGXT	P21549	RFX6	Homo sapiens	Q8HWS3	Validated Y2H	32296183
Intra	AGXT	P21549	RFX6	Homo sapiens	Q8HWS3	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FHL5	Homo sapiens	Q5TD97	Y2H Array	32296183
Intra	AGXT	P21549	FHL5	Homo sapiens	Q5TD97	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	FHL5	Homo sapiens	Q5TD97	Validated Y2H	32296183
Intra	AGXT	P21549	ATXN1L	Homo sapiens	P0C7T5	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	ATXN1L	Homo sapiens	P0C7T5	Y2H Array	32296183
Intra	AGXT	P21549	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	AGXT	P21549	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	AGXT	P21549	TTC19	Homo sapiens	Q6DKK2	Y2H Array	32296183
Intra	AGXT	P21549	TTC19	Homo sapiens	Q6DKK2	Y2H Prey Pooling	32296183
Intra	AGXT	P21549	TTC19	Homo sapiens	Q6DKK2	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

AGXT 抗体

製品番号	製品名	アプリケーション	反応性
HY-P82275	AGXT Antibody (YA2020)	WB	Mouse, Rat
HY-P82275A	AGXT Antibody (YA2020)(PBS only)	WB	Mouse, Rat

関連疾患

Diseases	Alias
Hyperoxaluria, Primary, Type I	Primary Hyperoxaluria Type 1 HP1 Glycolic Aciduria Alanine-Glyoxylate Aminotransferase Deficiency Hepatic Agt Deficiency Oxalosis I Primary Hyperoxaluria, Type I Serine:Pyruvate Aminotransferase Deficiency Hyperoxaluria, Primary, Type 1 Peroxisomal Alanine-Glyoxylate Aminotransferase Deficiency Peroxisomal Alanine Glyoxylate Aminotransferase Deficiency Serine Pyruvate Aminotransferase Deficiency Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency Oxalosis 1 Hyperoxaluria Primary 1 Hyperoxaluria Primary Type I Ph1 Primary Hyperoxaluria Type I Oxalosis Type 1 2-Oxoglutarate Glyoxylate Carboligase Deficiency
Primary Hyperoxaluria	Hyperoxaluria Hyperoxaluria, Primary Oxalosis Primary Oxalosis Congenital Oxaluria D-Glycerate Dehydrogenase Deficiency Glyceric Aciduria Glycolic Aciduria Hepatic Agt Deficiency Oxaluria, Primary Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency Primary Oxaluria Hyperoxaluria Primary Primary Hyperoxaluria Type 2 Primary Hyperoxaluria, Type I
Nephrocalcinosis	Hypercalcemic Nephropathy
Nephrolithiasis	Kidney Stones Stone - Kidney/Ureter Kidney Calculi
Urolithiasis
Hyperoxaluria, Primary, Type Ii	Primary Hyperoxaluria Type 2 D-Glycerate Dehydrogenase Deficiency Glyoxylate Reductase/Hydroxypyruvate Reductase Deficiency HP2 Oxalosis Ii Glyceric Aciduria L-Glyceric Aciduria Primary Hyperoxaluria, Type Ii Oxalosis 2 Hyperoxaluria Primary 2 Hyperoxaluria Primary Type Ii Ph2 Primary Hyperoxaluria Type Ii
Nephrolithiasis, Calcium Oxalate	Kidney Stones Calculus Of Kidney Kidney Calculi Nephrolithiasis Renal Calculi Calcium Oxalate Urolithiasis CAON Urolithiasis, Calcium Oxalate Calcium Oxalate Nephrolithiasis Kidney Stone Nephrolith Renal Calculus Urinary Stones Renal Stone Calculus, Kidney Calculus, Renal Renal Lithiasis Renal Stones Urolithiasis Renal Calculus Or Stone Stone In Kidney Nephritic Calculus Multiple Kidney Calculi Multiple Kidney Calculus Nephrolithiasis Nos Pelvic Nephrolithiasis Pelviolithiasis Pelvis Nephrolithiasis
Anterior Cerebral Artery Infarction	Infarction, Anterior Cerebral Artery
Nephrotic Syndrome	Finnish Congenital Nephrotic Syndrome Ns - [Nephrotic Syndrome] Nephrosis Syndrome Nephrosis Nos Glomerular Lesion Nephrosis
Hyperoxaluria, Primary, Type Iii	Primary Hyperoxaluria Type 3 HP3 Ph Iii Primary Hyperoxaluria Type Iii Hyperoxaluria Primary 3 Hyperoxaluria Non-Hp1/Non-Hp2 Hyperoxaluria Non-Ph I/Ph Ii Form Hyperoxaluria Primary Type Iii
Peroxisomal Disease	Peroxisomal Disorder Peroxisomal Disorders Peroxisomal Defects
End Stage Renal Disease	End Stage Renal Failure End-Stage Kidney Disease Kidney Failure, Chronic Chronic Kidney Disease Stage 5
Adenine Phosphoribosyltransferase Deficiency	Aprt Deficiency 2,8-Dihydroxyadenine Urolithiasis APRTD 2,8-Dihydroxyadeninuria Dihydroxyadeninuria Urolithiasis, 2,8-Dihydroxyadenine Urolithiasis, Dha Nephrolithiasis, Dha Dha Crystalline Nephropathy Nephrolithiasis Dha Urolithiasis Dha
Ureterolithiasis	Calculus Of Ureter Ureteric Stone Ureteral Calculi Ureteric Calculus Stone In The Ureter Ureter Calculi Ureteral Calculus Or Stone Ureterolith Ureterolithiasis Nos
Xanthinuria	Xanthine Dehydrogenase Deficiency Xanthine Oxidase Deficiency Hereditary Xanthinuria Xanthic Urolithiasis Xanthine Stone Disease Xanthinuria, Type I Combined Deficiency Of Xanthine Dehydrogenase And Aldehyde Oxidase Xdh Deficiency Classic Xanthinuria Xanthinuria, Type Ii Classical Xanthinuria Xanthine Calculus
Renal Tuberculosis	Tuberculosis, Renal Tuberculosis Of Kidney Tuberculosis Renal
Lower Urinary Tract Calculus	Calculus Of Lower Urinary Tract
Chronic Kidney Disease	Chronic Renal Disease Chronic Kidney Failure Ckd Chronic Renal Failure Kidney Failure, Chronic Chronic Renal Failure Syndrome Crf Renal Failure - Chronic Renal Failure Chronic Chronic Kidney Diseases Chronic Kidney Disease Stage 5 Ckd - [Chronic Kidney Disease] Crf - [Chronic Renal Failure] Chronic Kidney Impairment Chronic Renal Impairment Chronic Kidney Shutdown Chronic Hypoxic Kidney Failure Chronic Kidney Collapse Chronic Renal Insufficiency Chronic Kidney Toxaemia Chronic Kidney Hypofunction Chronic Renal Suppression Chronic Renal Failure, Stage 5 Ckd - [Chronic Kidney Disease] Stage 5 End Stage Kidney Failure End Stage Renal Failure End Stage Kidney Disease End Stage Renal Disease End Stage Chronic Renal Failure Esrf - [End Stage Renal Failure] Esrd - [End Stage Renal Diseases] Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²
Chromosome 2q37 Deletion Syndrome	Albright Hereditary Osteodystrophy-Like Syndrome 2q37 Microdeletion Syndrome Brachydactyly-Intellectual Disability Syndrome Deletion 2q37 2q37 Deletion Syndrome Brachydactyly-Mental Retardation Syndrome Bdmr Albright Hereditary Osteodystrophy Type 3 Del(2)(Q37) Monosomy 2q37qter Albright'S Hereditary Osteodystrophy-Like Syndrome Monosomy 2q37 Chromosome Deletion Syndrome 2q37
Spinocerebellar Ataxia 7	Spinocerebellar Ataxia Type 7 SCA7 Opca3 Opca Iii Olivopontocerebellar Atrophy Iii Opca With Retinal Degeneration Opca With Macular Degeneration And External Ophthalmoplegia Adca, Type Ii Autosomal Dominant Cerebellar Ataxia Type 2 Olivopontocerebellar Atrophy 3 Autosomal Dominant Cerebellar Ataxia, Type Ii Autosomal Dominant Cerebellar Ataxia Type Ii Adca2 Adcaii Ataxia With Pigmentary Retinopathy Cerebellar Syndrome-Pigmentary Maculopathy Syndrome Olivopontocerebellar Atrophy With Retinal Degeneration Spinocerebellar Ataxia-7 Ataxia, Spinocerebellar, Type 7
Purine-Pyrimidine Metabolic Disorder	Inborn Errors Of Purine-Pyrimidine Metabolism Disorder Of Purine Or Pyrimidine Metabolism
Cystinuria	CSNU Cystinuria Type B Cystinuria Type A Cystinuria, Type I, Formerly Csnu1, Formerly Cystinuria, Type Ii, Formerly Cystinuria, Type Iii, Formerly Csnu3, Formerly Cystinuria, Type Non-I, Formerly Cystinuria-Lysinuria Cystinuria-Lysinuria Syndrome Csnu1 Csnu3 Cystinuria 1 Cystinuria Type A/B Cystinuria Type I Cystinuria Type Ii Cystinuria Type Iii Cystinuria Type Non-I Cystinuria, Type A/B Cystinuria Type 1 Cystinuria - Lysinuria Csnu - [Cystinuria] Cystine Disease
Galloway-Mowat Syndrome 1	Galloway Syndrome Nephrosis-Neuronal Dysmigration Syndrome Nephrosis-Microcephaly Syndrome Camos Scar5 GAMOS1 Microcephaly, Hiatal Hernia, And Nephrotic Syndrome Microcephaly, Hiatal Hernia And Nephrotic Syndrome Cerebellar Ataxia With Mental Retardation, Optic Atrophy, And Skin Abnormalities Spinocerebellar Ataxia, Autosomal Recessive 5, Formerly Scar5, Formerly Spinocerebellar Ataxia Autosomal Recessive 5 Cerebellar Ataxia With Intellectual Disability Optic Atrophy And Skin Abnormalities Camos Syndrome Cerebellar Ataxia-Intellectual Disability-Optic Atrophy-Skin Abnormalities Syndrome Galloway-Mowat Syndrome Spinocerebellar Ataxia, Autosomal Recessive, 5 Galloway Mowat Syndrome Spinocerebellar Ataxia, Autosomal Recessive 5
Hemochromatosis, Type 1	Hemochromatosis Hemochromatosis Type 1 Hereditary Hemochromatosis Hh HFE1 Hfe Hemochromatosis, Modifier Of Symptomatic Form Of Classic Hemochromatosis Symptomatic Form Of Hemochromatosis Type 1 Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis Haemochromatosis Iron Storage Disorder Bronze Diabetes Hereditary Haemochromatosis Hlah Hfe Hemochromatosis, Hereditary Diabetes Bronze Classic Hemochromatosis Hfe-Associated Hereditary Hemochromatosis Hemochromatosis Classic Bronzed Cirrhosis Familial Hemochromatosis Genetic Hemochromatosis Hc Pigmentary Cirrhosis Primary Hemochromatosis Troisier-Hanot-Chauffard Syndrome Von Recklenhausen-Applebaum Disease Hemochromatosis 1 Primary Hereditary Hemochromatosis Bronze Cirrhosis
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-W023323	(S)-β-Aminoisobutyric acid hydrochloride		99.90%	Unkown
HY-159910	LH1513		/	Unkown
HY-RS00473	AGXT Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00474	AGXT2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Rattus norvegicus	AGXT	RGD	RGD:2073
Mus musculus	AGXT	MGD	MGI:1329033
Bos taurus	AGXT	VGNC	VGNC:25748
Felis catus	AGXT	VGNC	VGNC:59693
Macaca mulatta	AGXT	VGNC	VGNC:69756
Others	AGXT	NCBI