FADD - Fas associated via death domain Gene

Also Known as GIG3; IMD90; MORT1

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 8772

About FADD

Cytogenetic location: 11q13.3 Genomic coordinates (GRCh38): 11:70,203,296-70,207,390 (from NCBI)

This gene has 1 transcript (splice variant), 180 orthologues and is associated with 3 phenotypes. Ubiquitous expression in kidney (RPKM 9.3), colon (RPKM 8.7) and 25 other tissues.

Summary

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit Caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

FADD Products (1)

mRNA	Protein	Name
NM_003824.4	NP_003815.1	FAS-associated death domain protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables caspase binding	IDA IDA: Inferred from direct assay	24025841	GOA
enables caspase binding	IPI IPI: Inferred from physical interaction	9343261	GOA
enables death effector domain binding	IPI IPI: Inferred from physical interaction	11717445	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	7536190	GOA
enables protease binding	IPI IPI: Inferred from physical interaction	9208847	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7536190	GOA
enables protein-macromolecule adaptor activity	IDA IDA: Inferred from direct assay	8565075	GOA
enables tumor necrosis factor receptor superfamily binding	IPI IPI: Inferred from physical interaction	21109225	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in TRAIL-activated apoptotic signaling pathway	IDA IDA: Inferred from direct assay	21785459	GOA
involved in activation of cysteine-type endopeptidase activity	IDA IDA: Inferred from direct assay	18387192	GOA
involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	22891283	GOA
involved in apoptotic signaling pathway	IDA IDA: Inferred from direct assay	8565075	GOA
involved in cellular response to mechanical stimulus	IEP IEP: Inferred from expression pattern	19593445	GOA
involved in death-inducing signaling complex assembly	IDA IDA: Inferred from direct assay	24025841	GOA
involved in defense response to virus	IMP IMP: Inferred from mutant phenotype	21109225	GOA
involved in extrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	21785459	GOA
involved in extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	16611992	GOA
involved in extrinsic apoptotic signaling pathway via death domain receptors	IDA IDA: Inferred from direct assay	9184224	GOA
involved in necroptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	11101870	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	11821383	GOA
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	20935634	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IEP IEP: Inferred from expression pattern	12761501	GOA
involved in positive regulation of extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	21525013	GOA
involved in positive regulation of interleukin-8 production	IDA IDA: Inferred from direct assay	16127453	GOA
involved in positive regulation of macrophage differentiation	IMP IMP: Inferred from mutant phenotype	17047155	GOA
involved in positive regulation of proteolysis	IDA IDA: Inferred from direct assay	18387192	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	16127453	GOA
involved in positive regulation of tumor necrosis factor production	IDA IDA: Inferred from direct assay	16127453	GOA
involved in positive regulation of type I interferon-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	21109225	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
part of CD95 death-inducing signaling complex	IDA IDA: Inferred from direct assay	20935634	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	22510408	GOA
located in cytosol	IDA IDA: Inferred from direct assay	21785459	GOA
part of death-inducing signaling complex	IDA IDA: Inferred from direct assay	11101870	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	22510408	GOA
part of ripoptosome	IDA IDA: Inferred from direct assay	21737330	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FADD Protein Structure

DED

Death

0
100
208 a.a.

Protein Preferred Names	Protein Names
FAS-associated death domain protein	Fas (TNFRSF6)-associated via death domain

FADD Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	FADD	Q13158	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	UBE2I	Homo sapiens	Q7KZS0	Validated Y2H	32296183
Intra	FADD	Q13158	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	32296183
Intra	FADD	Q13158	FAM22F	Homo sapiens	B7ZLH0	Y2H Array	32296183
Intra	FADD	Q13158	FAM22F	Homo sapiens	B7ZLH0	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	PARK7	Homo sapiens	Q99497	Pull Down	21785459
Intra	FADD	Q13158	PARK7	Homo sapiens	Q99497	Anti Bait CoIP	21785459
Intra	FADD	Q13158	PARK7	Homo sapiens	Q99497	Anti Tag CoIP	21785459
Intra	FADD	Q13158	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	ZMYM5	Homo sapiens	Q9UJ78-2	Validated Y2H	32296183
Intra	FADD	Q13158	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Array	32296183
Intra	FADD	Q13158	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	FADD	Q13158	CASP8	Homo sapiens	Q14790-1	Anti Tag CoIP	8681376
Intra	FADD	Q13158	CASP8	Homo sapiens	Q14790-1	Y2H	8681376
Intra	FADD	Q13158	CASP8	Homo sapiens	Q14790-5	Anti Tag CoIP	8681376
Intra	FADD	Q13158	CASP8	Homo sapiens	Q14790-5	Y2H	8681376
Cross	FADD	Q13158	Fas	Mus musculus	P25446	X-Ray Diffraction	20935634
Cross	FADD	Q13158	Fas	Mus musculus	P25446	TEM	20935634
Cross	FADD	Q13158	Fas	Mus musculus	P25446	SLCA	20935634
Cross	FADD	Q13158	Fas	Mus musculus	P25446	Light Scattering	20935634
Cross	FADD	Q13158	Fas	Mus musculus	P25446	Pull Down	7536190
Cross	FADD	Q13158	Fas	Mus musculus	P25446	GMS	20935634
Cross	FADD	Q13158	Fas	Mus musculus	P25446	Pull Down	20935634
Intra	FADD	Q13158	MBD4	Homo sapiens	O95243	Y2H	12702765
Intra	FADD	Q13158	MBD4	Homo sapiens	O95243	CoIP	12702765
Intra	FADD	Q13158	MBD4	Homo sapiens	O95243	Pull Down	12702765
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	Validated Y2H	32296183
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	Anti Tag CoIP	33961781
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	Anti Bait CoIP	19524513
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	Anti Tag CoIP	19524513
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	Anti Bait CoIP	21458669
Intra	FADD	Q13158	RIPK1	Homo sapiens	Q13546	ViroTrap	30561431
Intra	FADD	Q13158	TRADD	Homo sapiens	Q15628	Y2H Array	32296183
Intra	FADD	Q13158	TRADD	Homo sapiens	Q15628	Validated Y2H	32296183
Intra	FADD	Q13158	TRADD	Homo sapiens	Q15628	Y2H	11112409
Intra	FADD	Q13158	TRADD	Homo sapiens	Q15628	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	MYD88	Homo sapiens	Q99836	Y2H	21988832
Intra	FADD	Q13158	PLK1	Homo sapiens	P53350	GMS	20890306
Intra	FADD	Q13158	PLK1	Homo sapiens	P53350	Confocal	20890306
Intra	FADD	Q13158	PLK1	Homo sapiens	P53350	Pull Down	20890306
Intra	FADD	Q13158	PLK1	Homo sapiens	P53350	Protein Kinase Assay	20890306
Intra	FADD	Q13158	FAS	Homo sapiens	P25445	Pull Down	7538907
Intra	FADD	Q13158	FAS	Homo sapiens	P25445	CoIP	7536190
Intra	FADD	Q13158	FAS	Homo sapiens	P25445	Anti Bait CoIP	21382479
Intra	FADD	Q13158	FAS	Homo sapiens	P25445	Anti Tag CoIP	16498403
Intra	FADD	Q13158	FASLG	Homo sapiens	P48023	PLA	25241761
Intra	FADD	Q13158	LRRK2	Homo sapiens	Q5S007	Anti Tag CoIP	19176810
Intra	FADD	Q13158	TCEA2	Homo sapiens	Q15560	Validated Y2H	32296183
Intra	FADD	Q13158	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	SDCBP	Homo sapiens	O00560	Y2H Array	32296183
Intra	FADD	Q13158	DDIT4L	Homo sapiens	Q96D03	Validated Y2H	32296183
Intra	FADD	Q13158	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	FADD	Q13158	BTG1	Homo sapiens	P62324	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	BTG1	Homo sapiens	P62324	Y2H Array	32296183
Intra	FADD	Q13158	ZCCHC12	Homo sapiens	Q6PEW1	Y2H Prey Pooling	32296183
Intra	FADD	Q13158	ZCCHC12	Homo sapiens	Q6PEW1	Validated Y2H	32296183
Intra	FADD	Q13158	ZCCHC12	Homo sapiens	Q6PEW1	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

FADD 抗体

製品番号	製品名	アプリケーション	反応性
HY-P811110	Phospho-FADD (Ser194) Antibody	WB, IHC-P	Human, Mouse, Rat
HY-P83048	FADD Antibody (YA2793)	WB, IHC-P	Human, Mouse
HY-P83048A	FADD Antibody (YA2793)(PBS only)	WB, IHC-P	Human, Mouse
HY-P85636	FADD Antibody (YA5328)	WB, ICC/IF, ELISA	Human

関連疾患

Diseases	Alias
Immunodeficiency 90 With Encephalopathy, Functional Hyposplenia, And Hepatic Dysfunction	Infections, Recurrent, With Encephalopathy, Hepatic Dysfunction, And Cardiovascular Malformations Fadd-Related Immunodeficiency IMD90 Fadd Deficiency Infections, Recurrent, Associated With Encephalopathy, Hepatic Dysfunction And Cardiovascular Malformations IEHDCM
Otodental Dysplasia	Otodental Syndrome Oculootodental Syndrome Chromosome 11q13 Deletion Syndrome Otodental Dysplasia Chromosome Deletion Syndrome Globodontia Ood
Molluscum Contagiosum	Water Warts Molluscum Verrucosum
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Lymphoproliferative Syndrome	Lymphoproliferative Disorder Lymphoproliferative Disorders Lymphoproliferative Disorders, Susceptibility To
Caspase 8 Deficiency	Autoimmune Lymphoproliferative Syndrome Type 2b Caspase-8 Deficiency Ceds Alps2b Autoimmune Lymphoproliferative Syndrome, Type Iib Alps With Recurrent Viral Infections Autoimmune Lymphoproliferative Syndrome With Recurrent Viral Infections Caspase 8 Deficiency Syndrome Caspase 8 Lymphadenopathy Syndrome Autoimmune Lymphoproliferative Syndrome Type Iib Caspase Eight Deficiency State CASP8D
Squamous Cell Carcinoma	Epidermoid Carcinoma Squamous Cell Cancer Carcinoma, Squamous Cell Squamous Cell Skin Cancer Malignant Squamous Cell Tumor Squamous Carcinoma Squamous Cell Epithelioma Carcinoma Squamous Cell Neoplasms, Squamous Cell Squamous Cell Carcinoma - Category Malignant Squamous Cell Neoplasm Squamous Cell Carcinoma Of Skin
Type 1 Diabetes Mellitus 4	Diabetes Mellitus, Insulin-Dependent, 4 Iddm4 Insulin-Dependent Diabetes Mellitus 4 T1D4 Insulin-Dependent Diabetes Mellitus-4
Ectodermal Dysplasia	Congenital Ectodermal Defect Congenital Ectodermal Dysplasia Ectodermal Dysplasia Syndrome Dysplasia, Ectodermal
Cervical Adenoid Cystic Carcinoma	Adenoid Cystic Carcinoma Of The Cervix Uteri
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Hypersensitivity Reaction Type Iv Disease	Immunoproliferative Disorders Immunoproliferative Disease
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (13)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-109582	ADT-OH		98.55%	Unkown
HY-14622	Necrostatin 2	Inhibitor	99.78%	Unkown
HY-148454	Necroptosis-IN-3	Inhibitor	99.53%	Unkown
HY-132203	Necrostatin-34	Inhibitor	98.90%	Unkown
HY-119369	FadD32 Inhibitor-1	Inhibitor	/	Unkown
HY-109582S	ADT-OH-d4		/	Unkown
HY-182307	OH14	Inducer	/	Unkown
HY-182597	Tracizoline		/	Unkown
HY-RS04665	FADD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-168770	Cl-Necrostatin-1	Inhibitor	/	Unkown
HY-RS17138	Fadd Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23584	Fadd Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W182790	Garsevil		/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Mus musculus	FADD	MGD	MGI:109324
Rattus norvegicus	FADD	RGD	RGD:628700
Felis catus	FADD	VGNC	VGNC:102880
Bos taurus	FADD	VGNC	VGNC:28700
Macaca mulatta	FADD	VGNC	VGNC:110502
Canis familiaris	FADD	VGNC	VGNC:51869
Others	FADD	NCBI